ArticleFluids and barriers of the CNS2014
Diverse arachnoid cyst morphology indicates different pathophysiological origins.
Article in Fluids and barriers of the CNS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- The role of age and Galassi type in management and surgical outcomes of pediatric middle fossa arachnoid cysts: a systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Pooled it
- Hypoglossal nerve palsy due to periarticular cyst extending into hypoglossal canal: a systematic review.Neurosurgical review · 2025Pooled it
- Unmasking the role of a thoracic arachnoid web and watershed ischemia in rapidly progressing paraplegia: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Crystal Violet Staining Facilitates Boundary Recognition in the Removal of Spinal Arachnoid Pathology.NMC case report journal · 2026Article
- Arachnoid cyst in the quadrigeminal cistern: A case from Afghanistan.Radiology case reports · 2024Article
- The Role of Aquaporin 1 in Water Retention Mechanism of Arachnoid Cysts: Insights from 3 Case Reports.The American journal of case reports · 2023Article
- Space-occupying brain lesions, trauma-related tau astrogliopathy, and ARTAG: a report of two cases and a literature review.Acta neuropathologica communications · 2021Review
- Prevalence and symptoms of intracranial arachnoid cysts: a population-based study.Journal of neurology · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are few, limited, and to some extent contradictory, reports on the cellular and subcellular morphology of arachnoid cysts. In the literature cyst membranes are described as similar to, or as vastly different from, normal arachnoid membranes.
methodsThis paper reports electron microscopic analyses of symptomatic cysts from 24 patients (12 males and 12 females; age 10-79), that underwent fenestration surgery. Fourteen cysts were located in the middle cranial fossa (temporal), one in the interpeduncular cistern, five in the posterior fossa, and four were overlying the frontal cortex.
resultsMicroscopic findings confirmed the diverse nature of this clinical condition. Twelve cyst walls resembled normal arachnoid, four had a conspicuous core of dense fibrous tissue with a simple epithelial lining, and the remaining aberrant cysts exhibited non-arachnoid luminal epithelia with plentiful microvilli and/or cilia, and also nervous tissue components in the wall. The possible identity and origin of various cyst types are discussed. We hypothesize that cysts are formed mostly at an early stage of embryonic development, as a teratological event.
conclusionsCysts with various epithelial linings and extracellular components most likely have different barrier properties and fluid turnover characteristics. Further studies are needed to elucidate relations between cyst morphology, fluid composition, pathogenesis, and clinical behaviour including growth rate and relapse tendency.
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