Evidence map›Paper›PMID 24580721›Full record

Trial reportThe journal of headache and pain2014

Headstrong intervention for pediatric migraine headache: a randomized clinical trial.

Michael A Rapoff, Mark Connelly, Jennifer L Bickel, Scott W Powers, Andrew D Hershey, Janelle R Allen, Cynthia W Karlson, Catrina C Litzenburg, John M Belmont

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The journal of headache and pain, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06387758 (Low Systemic/High Local Exercise Load in Pediatric Sickle Cell Disease), which is not on this map. Cited by 26 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06387758 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Low Systemic/High Local Exercise Load in Pediatric Sickle Cell Disease

TypeinterventionalSponsorUniversity of Mississippi Medical CenterRan2023 to 2025Enrolled60ConditionsSickle Cell Anemia in ChildrenArmsLow systemic strength training, Moderate systemic exercise
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael A RapoffUniversity of Kansas Medical Center, Department of Pediatrics, 3901 Rainbow Boulevard, Kansas City, KS 66160-7330, USA. mrapoff@kumc.edu.
Mark Connelly
Jennifer L Bickel
Scott W Powers
Andrew D Hershey
Janelle R Allen
Cynthia W Karlson
Catrina C Litzenburg
John M Belmont

Funding

Headstrong Intervention for Recurrent Pediatric HeadacheR01NS046641 · NINDS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI RAPOFF, MICHAEL ANDREW · 2004 to 2008
$633k
NINDS NIH HHS R01-NS046641
6 · The paper itself

Abstract

backgroundThe purpose of this study was to evaluate the efficacy of a self-guided CD-ROM program ("Headstrong") containing cognitive-behavioral self-management strategies versus an educational CD-ROM program for treating headaches, headache-related disability, and quality of life.

methodsParticipants were 35 children ages 7-12 years with migraine recruited from one university medical center and two children's hospital headache clinics. Participants were randomly assigned to complete the Headstrong or educational control CD-ROM program over a 4-week period. Data on headache frequency, duration, and severity, migraine-related disability, and quality of life (QOL) were obtained at baseline, post-intervention, and 3-months post-intervention.

resultsAt post-intervention, Headstrong resulted in lower severity (on a 10-point scale) than the control group by child report (5.06 ± 1.50 SD vs. 6.25 ± 1.92 SD, p = 0.03, ES = 0.7). At 3-months post-intervention, parents reported less migraine-related disability (on the PedMIDAS) in the Headstrong group compared to the control group (1.36 ± 2.06 SD vs. 5.18 ± 6.40 SD; p = 0.04, ES = 0.8). There were no other group differences at post treatment or at 3-months post-intervention.

conclusionsWhen compared to an educational control, Headstrong resulted in lower pain severity at post-treatment and less migraine-related disability at 3-months post-intervention, by child and parent report respectively. Headache frequency and quality of life did not change more for Headstrong versus control. Additional research is needed on the Headstrong Program to increase its efficacy and to test it with a larger sample recruited from multiple centers simultaneously.

Indexed as

CD-ROMSelf CareChildCognitive Behavioral TherapyEarly Medical InterventionFemaleHumansMaleMigraine DisordersPatient Education as TopicQuality of Life

Identifiers

PMID24580721
PMCPMC3996073

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.