Trial reportActa oto-laryngologica2014
Kinetic oscillation stimulation as treatment of non-allergic rhinitis: an RCT study.
Trial report in Acta oto-laryngologica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Variants of rhinitis medicamentosa treatment: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Pooled it
- Indomethacin has no effect on trigeminally provoked parasympathetic output.Cephalalgia : an international journal of headache · 2022Trial
- Kinetic oscillation stimulation as treatment of acute migraine: a randomized, controlled pilot study.Headache · 2015Trial
- Development, Factor Structure, and Preliminary Psychometric Evaluation of the Rhinitis Medicamentosa Questionnaire (RMQ) Among Topical Nasal Decongestant Users.Laryngoscope investigative otolaryngology · 2026Article
- Preserving Function, Enhancing Precision: The Rise of Personalized Endonasal Sinus Surgery.Cureus · 2025Review
- Does nose spray addiction exist? A qualitative analysis of addiction components in rhinitis medicamentosa.Journal of behavioral addictions · 2025Article
- On the nose: nasal neurostimulation as a technology countermeasure for sinonasal congestion in astronauts.Frontiers in physiology · 2025Article
- Trigeminal Function in Sino-Nasal Health and Disease.Biomedicines · 2023Review
- The effect of single kinetic oscillation stimulation treatment on nonallergic rhinitis.Laryngoscope investigative otolaryngology · 2023Article
- Achieving symptom relief in patients with myalgic encephalomyelitis by targeting the neuro-immune interface and optimizing disease tolerance.Oxford open immunology · 2023Article
- Applications of vibrational energy in the treatment of sinonasal disease: A scoping review.International forum of allergy & rhinology · 2022Article
- Cluster headache pathophysiology - insights from current and emerging treatments.Nature reviews. Neurology · 2021Review
- The cholinergic anti-inflammatory pathway in chronic kidney disease-review and vagus nerve stimulation clinical pilot study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Review
- Effects of intranasal kinetic oscillation stimulation on heart rate variability.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Article
- Resting-state fMRI study of acute migraine treatment with kinetic oscillation stimulation in nasal cavity.NeuroImage. Clinical · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
conclusionKinetic oscillation stimulation (KOS) of nasal mucosa at low frequency seems to be a possibly effective and safe short-term treatment of non-allergic nasal stuffiness.
objectiveTo assess the relief of rhinitis symptoms, especially stuffiness, by comparing active treatment, i.e. KOS at low frequency of the nasal mucosa, with placebo.
methodsPatients were randomized to active or placebo treatment in this double-blinded parallel design study. Treatment with an inflatable oscillating catheter was administered on day 0, and symptom scores (stuffiness, secretion, and itching) were graded daily until day 14. An overall grading of symptoms from 1 week before treatment and during 14 days thereafter was made at day 14. Eighty-six patients (52 with non-allergic perennial rhinitis, NAR; 34 with rhinitis medicamentosa, RM) were randomized, and 71 were evaluated (active treatment, n = 35; placebo, n = 36).
resultsPatients with either NAR or RM who received active treatment reported reduced symptom scores by some measures, e.g. median RQSS stuffiness measure fell from 2 to 1 on a scale from 0 to 3 during the week following treatment. No significant effect was observed for patients treated with placebo. Mild side effects were reported.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.