ArticleIranian Red Crescent medical journal2013
Serologic Detection of Anti Toxoplasma gondii Infection in Diabetic Patients.
Article in Iranian Red Crescent medical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Is chronic toxoplasmosis a risk factor for diabetes mellitus? A systematic review and meta-analysis of case-control studies.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesPooled it
- Public Health Implications of Latent Toxoplasmosis and Its Association With Type 2 Diabetes: A Case-Control Study in Qazvin, North-Western Iran.Health science reports · 2026Article
- Comparison of the performance of SAG2, GRA6, and GRA7 for serological diagnosis ofFrontiers in veterinary science · 2024Article
- Seroepidemiology ofJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Article
- Effects ofFood and waterborne parasitology · 2023Article
- Type-1 diabetes mellitus down-regulated local cerebral glial fibrillary acidic protein expression in experimental toxoplasmosis.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- Pancreatic Pathological Changes in Murine Toxoplasmosis and Possible Association with Diabetes Mellitus.Biomedicines · 2022Article
- The Immune Response in Adipocytes and Their Susceptibility to Infection: A Possible Relationship with Infectobesity.International journal of molecular sciences · 2022Review
- Graph Embedding Based Novel Gene Discovery Associated With Diabetes Mellitus.Frontiers in genetics · 2021Article
- Development of Nano-ELISA Method for Serological Diagnosis of Toxoplasmosis in Mice.Archives of Razi Institute · 2021Article
- First Age- and Gender-Matched Case-Control Study in Australia Examining the Possible Association betweenJournal of parasitology research · 2020Article
- The association between Toxoplasma gondii infection and hypertensive disorders in T2DM patients: a case-control study in the Han Chinese population.Parasitology research · 2018Article
- Article
- Lack of Association BetweenJournal of clinical medicine research · 2017Article
- Prevalence of toxoplasmosis and related risk factors among humans referred to main laboratories of Urmia city, North West of Iran, 2013.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016Article
- Detection of Toxoplasma gondii in Diabetic Patients Using the Nested PCR Assay via RE and B1 Genes.Jundishapur journal of microbiology · 2016Article
- Toxoplasmosis, Pancreatitis, Obesity and Drug Discovery.Pancreatic disorders & therapy · 2014Article
- The Correlation between Serum Levels of Anti-Iranian journal of parasitologyArticle
- Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India.International journal of health sciencesArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundToxoplasmosis is caused by the Toxoplasma gondii parasite. The parasite is intracellular and can result in severe complications leading to death in immuno-deficient patients in particular. Diabetes is an important factor that increases susceptibility and risk of various infections in the host.
objectivesThe present study focused on the serologic detection of Toxoplasma gondii infection in diabetic patients. MATERIALS AND
methodsThrough a case-control study, overall 184 serum samples including 91 from diabetic cases and 93 from healthy non-diabetic controls were investigated. Cases and controls were matched for age and gender. Serum samples were tested for sugar by an enzymatic method, and IgG antibodies were tested against Toxoplasma gondii by ELISA method.
resultsThe prevalence of IgG antibodies against Toxoplasma gondii in diabetic patients and healthy controls were 60.43% and 38% respectively. Risk of toxoplasmosis infection in diabetic patients with was two folds higher than healthy controls (RR = 2.21, 95% CI; 1.6 - 3.7, P = 0.001).
conclusionsDiabetes may be caused by Toxoplasma gondii. Presence of T. gondii in the pancreas at the same time could directly undermines the pancreas cells. When β cells are destroyed, insulin secretion would then be affected. Probably the destruction of T. gondii affects nervous system and damages pancreatic cells leading to increased risk of diabetes.
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