Evidence map›Paper›PMID 24578634›Full record

ArticleTheScientificWorldJournal2014

A web-server of cell type discrimination system.

Anyou Wang, Yan Zhong, Yanhua Wang, Qianchuan He

Abstract read
In one paragraph

Article in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anyou WangLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27514, USA.ORCID 0000-0002-4981-3606
Yan ZhongLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27514, USA ; Division of Gynecologic Oncology, Linyi Tumor Hospital, Shandong 276000, China.
Yanhua WangDepartment of Probability and Statistics, School of Mathematics, Beijing Institute of Technology, Beijing 100081, China.ORCID 0000-0001-5654-9164
Qianchuan HePublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.ORCID 0000-0001-7044-6591

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discriminating cell types is a daily request for stem cell biologists. However, there is not a user-friendly system available to date for public users to discriminate the common cell types, embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and somatic cells (SCs). Here, we develop WCTDS, a web-server of cell type discrimination system, to discriminate the three cell types and their subtypes like fetal versus adult SCs. WCTDS is developed as a top layer application of our recent publication regarding cell type discriminations, which employs DNA-methylation as biomarkers and machine learning models to discriminate cell types. Implemented by Django, Python, R, and Linux shell programming, run under Linux-Apache web server, and communicated through MySQL, WCTDS provides a friendly framework to efficiently receive the user input and to run mathematical models for analyzing data and then to present results to users. This framework is flexible and easy to be expended for other applications. Therefore, WCTDS works as a user-friendly framework to discriminate cell types and subtypes and it can also be expended to detect other cell types like cancer cells.

Indexed as

Cytological TechniquesInternetModels, TheoreticalProgramming LanguagesSoftware DesignAdultAnimalsHumans

Identifiers

PMID24578634
PMCPMC3919083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.