Trial reportPrenatal diagnosis2014
A randomized trial of a prenatal genetic testing interactive computerized information aid.
Trial report in Prenatal diagnosis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07077707 (A Randomized Trial of Chatbot for Prenatal Genetic Counseling), which is not on this map. Cited by 35 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial of Chatbot for Prenatal Genetic Counseling
Who cites it
35 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024Pooled it
- Effectiveness of Interactive Digital Decision Aids in Prenatal Screening Decision-making: Systematic Review and Meta-analysis.Journal of medical Internet research · 2023Pooled it
- Decision coaching for people making healthcare decisions.The Cochrane database of systematic reviews · 2021Pooled it
- Health Literacy in Pregnant Women: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Interventions to Improve Health among Reproductive-Age Women of Low Health Literacy: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Use of Decision Support Tools to Empower Pregnant Women: Systematic Review.Journal of medical Internet research · 2020Pooled it
- A Systematic Review of Randomized Controlled Trials to Assess Outcomes of Genetic Counseling.Journal of genetic counseling · 2017Pooled it
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2017Pooled it
- Health Literacy and Women's Reproductive Health: A Systematic Review.Journal of women's health (2002) · 2016Pooled it
- Exploring measurement tools used to assess knowledge, attitudes, and perceptions of pregnant women toward prenatal screening: A systematic review.Women's health (London, England)Pooled it
- Health Literacy among Pregnant Women in a Lifestyle Intervention Trial.International journal of environmental research and public health · 2022Trial
- Digital vs face-to-face information provision in patient counselling for prenatal screening: A noninferiority randomized controlled trial.Prenatal diagnosis · 2019Trial
- Improving Patient Knowledge of Aneuploidy Testing Using an Educational Video: A Randomized Controlled Trial.Obstetrics and gynecology · 2018Trial
- Online Module for Carrier Screening in Ashkenazi Jewish Individuals Compared with In-Person Genetics Education: A Randomized Controlled Trial.Journal of genetic counseling · 2018Trial
- Digital genetic counseling services for cascade cardiogenetic testing.Journal of genetic counseling · 2026Article
- Respectful Patient-Provider Communication and Patient Portal Usage in Pregnant People of Color.Health equity · 2025Article
- Evaluating the Applied Knowledge of BRCA Testing among Spanish-Preferring Latino Americans: The Influence of Acculturation and Literacy.Public health genomics · 2025Article
- Self-care practices during pregnancy and associated factors among pregnant mothers who attended and underwent follow-up at public health facilities in Jimma Town, Oromia, Southwest Ethiopia, in 2023.Frontiers in global women's health · 2025Article
- Picture this: Evaluating the efficacy of genetic counseling visual aids.Journal of genetic counseling · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectiveThe aim of this study was to determine whether an interactive computer program could improve patient knowledge regarding genetic screening and diagnostic concepts.
methodsIn this randomized trial, women 6-26 weeks' gestation were assigned to standard care with provider-based counseling or to augmented counseling with an interactive computer program. The computer-based tool conveyed information about genetic testing options. Women were administered a 23-item test of content knowledge immediately and 2-4 weeks after exposure. Test scores were compared between groups at both points using T-tests.
resultsA total of 150 women were randomized equally between groups. Groups were similar with regard to demographic characteristics. Women randomized to the interactive tool correctly answered a significantly greater proportion of questions than those who received standard counseling (69.4% ± 14.2% vs. 46.0% ± 15.2%, p < 0.001) on the immediate questionnaire. One hundred and twenty-three (82%) participants participated in the follow-up test. Women randomized to the tool continued to correctly answer a significantly greater proportion of questions (60.6% ± 16% vs. 49.7% ± 18.9%, p = 0.001). Education, health literacy, electronic health literacy, and other discussions with providers were not associated with a differential benefit from the educational intervention.
conclusionA patient-directed interactive computer program may help providers to convey relevant information about genetic screening and diagnostic concepts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.