Evidence map›Paper›PMID 24577949›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2014

Impact of right-ventricular apical pacing on the optimal left-ventricular lead positions measured by phase analysis of SPECT myocardial perfusion imaging.

Guang-Uei Hung, Jin-Long Huang, Wan-Yu Lin, Shih-Chung Tsai, Kuo-Yang Wang, Shih-Ann Chen, Michael S Lloyd, Ji Chen

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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Clinical impacts of scar reduction on gated myocardial perfusion SPECT after cardiac resynchronization therapy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  2. Article
  3. Prognostic value of phase analysis on gated single photon emission computed tomography in patients with cardiac sarcoidosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  4. Review
  5. Impact of cardiac reverse remodeling after cardiac resynchronization therapy assessed by myocardial perfusion imaging on ventricular arrhythmia.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  6. Observational
  7. Biventricular pacing in heart failure: right is not wrong!European journal of nuclear medicine and molecular imaging · 2014
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Guang-Uei HungChang Bing Show Chwan Memorial Hospital, Changhua, Taiwan.
Jin-Long Huang
Wan-Yu Lin
Shih-Chung Tsai
Kuo-Yang Wang
Shih-Ann Chen
Michael S Lloyd
Ji Chen

Funding

Measuring Left Ventricular Dyssynchrony from ECG-gated Myocardial Perfusion SPECTR01HL094438 · NHLBI · EMORY UNIVERSITY · PI CHEN, JI · 2009 to 2012
$1.5M
NHLBI NIH HHS 1R01HL094438
6 · The paper itself

Abstract

purposeThe use of SPECT phase analysis to optimize left-ventricular (LV) lead positions for cardiac resynchronization therapy (CRT) was performed at baseline, but CRT works as simultaneous right ventricular (RV) and LV pacing. The aim of this study was to assess the impact of RV apical (RVA) pacing on optimal LV lead positions measured by SPECT phase analysis.

methodsThis study prospectively enrolled 46 patients. Two SPECT myocardial perfusion scans were acquired under sinus rhythm with complete left bundle branch block and RVA pacing, respectively, following a single injection of (99m)Tc-sestamibi. LV dyssynchrony parameters and optimal LV lead positions were measured by the phase analysis technique and then compared between the two scans.

resultsThe LV dyssynchrony parameters were significantly larger with RVA pacing than with sinus rhythm (p ~0.01). In 39 of the 46 patients, the optimal LV lead positions were the same between RVA pacing and sinus rhythm (kappa = 0.861). In 6 of the remaining 7 patients, the optimal LV lead positions were along the same radial direction, but RVA pacing shifted the optimal LV lead positions toward the base.

conclusionThe optimal LV lead positions measured by SPECT phase analysis were consistent, no matter whether the SPECT images were acquired under sinus rhythm or RVA pacing. In some patients, RVA pacing shifted the optimal LV lead positions toward the base. This study supports the use of baseline SPECT myocardial perfusion imaging to optimize LV lead positions to increase CRT efficacy.

Indexed as

Cardiac-Gated Single-Photon Emission Computer-Assisted TomographyMyocardial Perfusion ImagingAgedArrhythmia, SinusCardiac Resynchronization TherapyFemaleHumansMaleMiddle AgedRadiopharmaceuticalsTechnetium Tc 99m SestamibiVentricular Function, LeftVentricular Function, RightRadiopharmaceuticalsTechnetium Tc 99m Sestamibi

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.