ArticleEuropean journal of applied physiology2014
The detection and measurement of interleukin-6 in venous and capillary blood samples, and in sweat collected at rest and during exercise.
Article in European journal of applied physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 36 citations in OpenAlex.
- Mapping Multi-Modal Fatigue in Elite Soccer Through Sweat-Omics Perspectives: A Narrative Review.Biology · 2025Review
- Acute response of biomarkers in plasma from capillary blood after a strenuous endurance exercise bout.European journal of applied physiology · 2023Article
- Physiological mechanisms determining eccrine sweat composition.European journal of applied physiology · 2020Review
- Article
- Conformal and Disposable Antenna-Based Sensor for Non-Invasive Sweat Monitoring.Sensors (Basel, Switzerland) · 2018Article
- The impact of sleep restriction while performing simulated physical firefighting work on cortisol and heart rate responses.International archives of occupational and environmental health · 2016Article
- Relationships between inflammatory cytokine and cortisol responses in firefighters exposed to simulated wildfire suppression work and sleep restriction.Physiological reports · 2015Article
- The Impact of Sleep Restriction and Simulated Physical Firefighting Work on Acute Inflammatory Stress Responses.PloS one · 2015Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to quantify the relationship between venous and capillary blood sampling methods for the measurement of plasma interleukin-6 (IL-6). A parallel study was conducted to determine the possibility of measuring IL-6 in sweat using an enzyme-linked immunosorbent assay (ELISA) and investigate the relationship between plasma- and sweat-derived measures of IL-6.
methodsTwelve male participants were recruited for the measurement of IL-6 at rest and during exercise (study 1). An additional group of five female participants was recruited for the measurement of IL-6 in venous blood versus sweat at rest and following exercise (study 2). In study 1, venous and capillary blood samples were collected at rest and in response to exercise. In study 2, venous and sweat samples were collected following exercise.
resultsMean plasma IL-6 concentration was not different between venous and capillary blood sampling methods either at rest (4.27 ± 5.40 vs. 4.14 ± 4.45 pg ml(-1)), during (5.40 ± 5.17 vs. 5.58 ± 6.34 pg ml(-1)), or in response to exercise (6.95 ± 6.37 vs. 6.99 ± 6.74 pg ml(-1)). There was no IL-6 detectable in sweat either at rest or following exercise.
conclusionThere are no differences in the measurement of plasma IL-6 using either venous or capillary blood sampling methods. Capillary measurement represents a minimally invasive way of measuring IL-6 and detecting changes in IL-6, which are linked to fatigue and overtraining.
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