ArticleCurrent microbiology2014
Differential expression of two-component systems, pmrAB and phoPQ, with different growth phases of Klebsiella pneumoniae in the presence or absence of colistin.
Article in Current microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Adaptive colistin resistance dynamics inMicrobiology spectrum · 2026Article
- Nationwide genomic surveillance of carbapenem- and colistin-resistant Klebsiella pneumoniae bloodstream isolates in Thailand (2020-2024).Scientific reports · 2026Article
- Colistin Resistance Mechanisms and Molecular Epidemiology ofInfection and drug resistance · 2024Article
- Review
- Combined effect of Polymyxin B and Tigecycline to overcome Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae.Microbiology spectrum · 2021Article
- Detection of colistin-resistant populations prior to antibiotic exposure in KPC-2-producing Klebsiella pneumoniae clinical isolates.Journal of microbiology (Seoul, Korea) · 2021Article
- Multifaceted mechanisms of colistin resistance revealed by genomic analysis of multidrug-resistant Klebsiella pneumoniae isolates from individual patients before and after colistin treatment.The Journal of infection · 2019Article
- Colistin Heteroresistance inJournal of clinical medicine · 2019Article
- Multidrug-resistant Klebsiella pneumoniae: genetic diversity, mechanisms of resistance to polymyxins and clinical outcomes in a tertiary teaching hospital in Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2019Article
- PmrAB and PhoPQ Variants in Colistin-Resistant Enterobacter spp. Isolates in Korea.Current microbiology · 2019Article
- Fitness cost of mcr-1-mediated polymyxin resistance in Klebsiella pneumoniae.The Journal of antimicrobial chemotherapy · 2018Article
- Clinical Pharmacokinetics and Pharmacodynamics of Colistin.Clinical pharmacokinetics · 2017Review
- Clinical Implications of Genomic Adaptation and Evolution of Carbapenem-Resistant Klebsiella pneumoniae.The Journal of infectious diseases · 2017Review
- Mechanisms of Increased Resistance to Chlorhexidine and Cross-Resistance to Colistin following Exposure of Klebsiella pneumoniae Clinical Isolates to Chlorhexidine.Antimicrobial agents and chemotherapy · 2017Article
- Loss of hypermucoviscosity and increased fitness cost in colistin-resistant Klebsiella pneumoniae sequence type 23 strains.Antimicrobial agents and chemotherapy · 2015Article
- Genomic and transcriptomic analyses of colistin-resistant clinical isolates of Klebsiella pneumoniae reveal multiple pathways of resistance.Antimicrobial agents and chemotherapy · 2015Article
- Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria.Frontiers in microbiology · 2014Review
- Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We explored whether expression of pmrAB, pmrD, and phoPQ is dependent on growth phase with or without colistin exposure in colistin-resistant Klebsiella pneumoniae strains. In four colistin-resistant K. pneumoniae strains, the expression of pmrAB, pmrD, and phoPQ was evaluated at mid-log, late-log, and stationary phases in the absence or presence of colistin, by qRT-PCR. The expression pattern in the presence of colistin was different from that in the absence of colistin: overall, pmrAB, pmrD, and phoPQ expressed the highest at the stationary phase in the absence of colistin, but the expression of pmrD and phoPQ decreased with the growth in the presence of colistin. Exposure to colistin might change the expression patterns of two-component regulatory systems in colistin-resistant K. pneumoniae strains.
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