Evidence map›Paper›PMID 24577287›Full record

Trial reportThe American journal of psychiatry2014

Computer-assisted delivery of cognitive-behavioral therapy: efficacy and durability of CBT4CBT among cocaine-dependent individuals maintained on methadone.

Kathleen M Carroll, Brian D Kiluk, Charla Nich, Melissa A Gordon, Galina A Portnoy, Daniel R Marino, Samuel A Ball

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 14 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 14 syntheses or guidelines pooled it, 177 citations in OpenAlex.

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  5. Psychosocial interventions for stimulant use disorder.The Cochrane database of systematic reviews · 2024
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  20. Evaluating a longitudinal mediation model of perceived stress, depressive symptoms, and substance use treatment outcomes.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kathleen M Carroll
Brian D Kiluk
Charla Nich
Melissa A Gordon
Galina A Portnoy
Daniel R Marino
Samuel A Ball
Yale University · US

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
Computer-Based Training in Cognitve Behavioral TherapyR01DA015969 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2002 to 2015
$2.8M
Computer-Based Training in Cognitve Behavioral TherapyR37DA015969 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2003 to 2009
$2.6M
NIDA NIH HHS P50 DA009241NIDA NIH HHS P50-DA09241NIDA NIH HHS R01 DA015969NIDA NIH HHS R37 DA015969NIDA NIH HHS R37-DA015969
6 · The paper itself

Abstract

objectiveA previous pilot trial evaluating computer-based training for cognitive-behavioral therapy (CBT4CBT) in 77 heterogeneous substance users (alcohol, marijuana, cocaine, and opioids) demonstrated preliminary support for its efficacy in the context of a community-based outpatient clinic. The authors conducted a more definitive trial in a larger, more homogeneous sample.

methodIn this randomized clinical trial, 101 cocaine-dependent individuals maintained on methadone were randomly assigned to standard methadone maintenance or methadone maintenance with weekly access to CBT4CBT, with seven modules delivered within an 8-week trial.

resultsTreatment retention and data availability were high and comparable across the treatment conditions. Participants assigned to the CBT4CBT condition were significantly more likely to attain 3 or more consecutive weeks of abstinence from cocaine (36% compared with 17%; p<0.05, odds ratio=0.36). The group assigned to CBT4CBT also had better outcomes on most dimensions, including urine specimens negative for all drugs, but these reached statistical significance only for individuals completing the 8-week trial (N=69). Follow-up data collected 6 months after treatment termination were available for 93% of the randomized sample; these data indicate continued improvement for those assigned to the CBT4CBT group, replicating previous findings regarding its durability.

conclusionsThis trial replicates earlier findings indicating that CBT4CBT is an effective adjunct to addiction treatment with durable effects. CBT4CBT is an easily disseminable strategy for broadening the availability of CBT, even in challenging populations such as cocaine-dependent individuals enrolled in methadone maintenance programs.

Indexed as

AdultCocaine-Related DisordersCognitive Behavioral TherapyCombined Modality TherapyFemaleHumansMaleMethadoneMiddle AgedNarcoticsTherapy, Computer-AssistedTreatment OutcomeMethadoneNarcotics

Identifiers

PMID24577287
PMCPMC4042674
OpenAlexW2166556467

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.