ArticleMedical mycology2014
Characterization of Alternaria infectoria extracellular vesicles.
Article in Medical mycology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 94 citations in OpenAlex.
- Extracellular Vesicles: Key Mediators of Bioactive Molecule Transport in Plant-Microbe Interactions.Molecular plant pathology · 2026Review
- Establishment of an Isolation System for Extracellular Vesicles ofJournal of fungi (Basel, Switzerland) · 2025Article
- Isolation and Characterization of Extracellular Vesicles From Ascochyta rabiei, a Necrotrophic Fungal Chickpea Pathogen.Proteomics · 2025Article
- Unlocking the agro-physiological potential of wheat rhizoplane fungi under low P conditions using a niche-conserved consortium approach.Journal of experimental botany · 2025Article
- Flowering Plant Microbiomes and Network Interactions Across an Urban Gradient.Environmental microbiology · 2025Article
- Characterizing extracellular vesicles of human fungal pathogens.Nature microbiology · 2025Review
- Review
- Isolation, Characterization, and Proteomic Analysis of Crude and Purified Extracellular Vesicles Extracted fromPlants (Basel, Switzerland) · 2024Article
- Extracellular Vesicles fromJournal of fungi (Basel, Switzerland) · 2024Article
- The Adaptation ofJournal of fungi (Basel, Switzerland) · 2023Article
- Characteristics and potential clinical applications of the extracellular vesicles of human pathogenic Fungi.BMC microbiology · 2023Review
- Article
- Extracellular Vesicles of the Plant PathogenJournal of fungi (Basel, Switzerland) · 2023Article
- First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale.IMA fungus · 2023Article
- Fungal extracellular vesicle-mediated regulation: from virulence factor to clinical application.Frontiers in microbiology · 2023Review
- Extracellular vesicles in phytopathogenic fungi.Extracellular vesicles and circulating nucleic acids · 2023Review
- Extracellularly Released Molecules by the Multidrug-Resistant Fungal Pathogens Belonging to theJournal of fungi (Basel, Switzerland) · 2022Review
- Isolation and characterization of extracellular vesicles from biotechnologically important fungus Aureobasidium pullulans.Fungal biology and biotechnology · 2022Article
- The RNA Content of Fungal Extracellular Vesicles: At the "Cutting-Edge" of Pathophysiology Regulation.Cells · 2022Review
- Extracellular vesicles: Their functions in plant-pathogen interactions.Molecular plant pathology · 2022Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
Many fungi use membrane vesicles to transport complex molecules across their cell walls. Like mammalian exosomes, fungal vesicles contain lipids, proteins, and polysaccharides, many of which are associated with virulence. Here we identify and characterize extracellular vesicles (EVs) in Alternaria infectoria, a ubiquitous, environmental filamentous fungus that is also an opportunistic human pathogen. Examination of the A. infectoria EVs revealed a morphology similar to that of vesicles described in other fungal species. Of note, proteomic analysis detected a reduced number of vesicle-associated proteins. There were two prevalent categories among the 20 identified proteins, including the polysaccharide metabolism group, probably related to plant host invasion or biosynthesis/degradation of cell wall components, and the nuclear proteins, especially DNA repair enzymes. We also found enzymes related to pigment synthesis, adhesion to the host cell, and trafficking of vesicles/organelles/molecules. This is the first time EV secretions have been identified in a filamentous fungus. We believe that these vesicles might have a role in virulence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.