ReviewMethods (San Diego, Calif.)2014
RNAi screening in Drosophila cells and in vivo.
Review in Methods (San Diego, Calif.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- An image-based RNAi screen identifies the EGFR signaling pathway as a regulator of Imp RNP granules.Journal of cell science · 2024Article
- Article
- Serum-free adapted Drosophila S2R+ line is amenable to RNA interference.microPublication biology · 2021Article
- Genetics in Light of Transcriptional Adaptation.Trends in genetics : TIG · 2020Review
- Daywake, an Anti-siesta Gene Linked to a Splicing-Based Thermostat from an Adjoining Clock Gene.Current biology : CB · 2019Article
- Generating and working with Drosophila cell cultures: Current challenges and opportunities.Wiley interdisciplinary reviews. Developmental biology · 2019Review
- Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster.Neurotoxicity research · 2018Article
- Defense Mechanisms against Viral Infection inViruses · 2018Review
- RNA Interference (RNAi) Screening inGenetics · 2018Article
- Optimized strategy for in vivo Cas9-activation inProceedings of the National Academy of Sciences of the United States of America · 2017Article
- RNAi-Mediated Reverse Genetic Screen IdentifiedG3 (Bethesda, Md.) · 2017Article
- Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration.Molecular and cellular neurosciences · 2017Review
- Review
- RNAi-Based Techniques for the Analysis of Gene Function in Drosophila Germline Stem Cells.Methods in molecular biology (Clifton, N.J.) · 2017Article
- Loss-of-function genetic tools for animal models: cross-species and cross-platform differences.Nature reviews. Genetics · 2017Review
- Regionalization of surface lipids in insects.Proceedings. Biological sciences · 2016Article
- Drosophila tools and assays for the study of human diseases.Disease models & mechanisms · 2016Review
- Article
- Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells.G3 (Bethesda, Md.) · 2015Article
- A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases.Cell · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Here, I discuss how RNAi screening can be used effectively to uncover gene function. Specifically, I discuss the types of high-throughput assays that can be done in Drosophila cells and in vivo, RNAi reagent design and available reagent collections, automated screen pipelines, analysis of screen results, and approaches to RNAi results verification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.