Evidence map›Paper›PMID 24576395›Full record

Trial reportPreventing chronic disease2014

Diabetes prevention in Hispanics: report from a randomized controlled trial.

Catherine Duggan, Elizabeth Carosso, Norma Mariscal, Ilda Islas, Genoveva Ibarra, Sarah Holte, Wade Copeland, Sandra Linde, Beti Thompson

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Preventing chronic disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Systematic Review of Physical Activity Interventions in Hispanic Adults.Hispanic health care international : the official journal of the National Association of Hispanic Nurses · 2018
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Mediators and Moderators of Improvements in Medication Adherence.Health education & behavior : the official publication of the Society for Public Health Education · 2017
    Trial
  5. Article
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  8. Review
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  11. How patient and community involvement in diabetes research influences health outcomes: A realist review.Health expectations : an international journal of public participation in health care and health policy · 2019
    Review
  12. Considerations and guidance in designing equity-relevant clinical trials.International journal for equity in health · 2017
    Article
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catherine DugganPublic Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave, N Seattle, WA 98109. E-mail: cduggan@fhcrc.org.
Elizabeth CarossoFred Hutchinson Cancer Research Center, N Seattle, Washington.
Norma MariscalFred Hutchinson Cancer Research Center, N Seattle, Washington.
Ilda IslasFred Hutchinson Cancer Research Center, N Seattle, Washington.
Genoveva IbarraFred Hutchinson Cancer Research Center, N Seattle, Washington.
Sarah HolteFred Hutchinson Cancer Research Center, N Seattle, Washington.
Wade CopelandFred Hutchinson Cancer Research Center, N Seattle, Washington.
Sandra LindeSunnyside Community Hospital, Sunnyside, Washington.
Beti ThompsonFred Hutchinson Cancer Research Center and University of Washington, Seattle, Washington.

Funding

Partnership for a Hispanic Diabetes Prevention ProgramR24MD001621 · NIMHD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI THOMPSON, BETI · 2005 to 2012
$4.2M
NIMHD NIH HHS R24 MD 001621NIMHD NIH HHS R24 MD001621
6 · The paper itself

Abstract

introductionHispanics are at increased risk of developing type 2 diabetes. Lifestyle interventions are effective in preventing diabetes and restoring glucose regulation.

methodsWe recruited Hispanic men and women (N = 320) who were residents of the Lower Yakima Valley, Washington, aged 18 years or older with hemoglobin A1c (HbA1c) levels higher than 6% to a parallel 2-arm randomized-controlled trial conducted from 2008 through 2012. The trial compared participants in the intervention arm, who received an immediate educational curriculum (n = 166), to participants in the control arm, who received a delayed educational curriculum (n = 154). The home-based curriculum consisted of 5 sessions led by community health workers and was designed to inform participants about diabetes, diabetes treatment, and healthy dietary and physical activity behaviors. Participants were randomly assigned to the intervention and control arms, and analysts were blinded as to participant arm. We evaluated intervention effects on HbA1c levels; frequency (times per week) of fruit and vegetable consumption; and frequency (times per week) of mild, moderate, and strenuous leisure-time physical activity. At baseline, 3 months, and 6 months after randomization, participants completed a questionnaire and provided a blood sample. Analysts were blinded to intervention arm.

resultsThe immediate intervention group (-0.64% [standard error (SE) 0.10]) showed a significant improvement in HbA1c scores (-37.5%, P = .04) compared with the delayed intervention group (-0.44%, P = .14). No significant changes were seen for dietary end points or changes in physical activity. We did observe a trend of greater increases in frequency of moderate and vigorous physical activity and a smaller increase in mild physical activity in the immediate intervention group than in the delayed intervention group.

conclusionThis home-based intervention delivered by CHWs was associated with a clinically and statistically significant reduction in HbA1c levels in Hispanic adults with HbA1c levels higher than 6%.

Indexed as

DietHispanic or LatinoMotor ActivityDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansMaleMiddle AgedGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID24576395
PMCPMC3938962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.