Evidence map›Paper›PMID 24575549›Full record

ReviewPediatric endocrinology reviews : PER2013

Measuring growth hormone and insulin-like growth factor-I in infants: what is normal?

Colin Patrick Hawkes, Adda Grimberg

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric endocrinology reviews : PER, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Provocative growth hormone testing in children: how did we get here and where do we go now?Journal of pediatric endocrinology & metabolism : JPEM · 2021
    Review
  8. Important Tools for Use by Pediatric Endocrinologists in the Assessment of Short StatureJournal of clinical research in pediatric endocrinology · 2021
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Neonatal Hypopituitarism: Approaches to Diagnosis and TreatmentJournal of clinical research in pediatric endocrinology · 2019
    Review
  17. Observational
  18. Intermittent hypoxia suppression of growth hormone and insulin-like growth factor-I in the neonatal rat liver.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Colin Patrick HawkesDivision of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Adda GrimbergDivision of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Children's Hospital of Philadelphia · US

Funding

Overcoming Disparities in Growth EvaluationsR01HD057037 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI GRIMBERG, ADDA · 2009 to 2012
$2.1M
NICHD NIH HHS 1R01 HD57037NICHD NIH HHS R01 HD057037
6 · The paper itself

Abstract

The role of growth hormone (GH) and insulinlike growth factor-I (IGF-I) change through early childhood. Whereas poor growth is a later presenting feature, infants with isolated GH deficiency have a normal birth weight and length, and often present with hypoglycemia. IGF-I plays an important role antenatally and post-natally in somatic and brain growth. In order to evaluate the GH/IGF-I axis in infancy, an understanding of the normal physiology is required. Measurements of GH and IGF-I in this population should be interpreted in the context of the assays used, as well as their limitations. In this review, we summarize our current understanding of normal GH and IGF-I secretion in children under 18 months of age, and describe variations in the reported assay-specific measurements.

Indexed as

Age FactorsDiagnostic Techniques, EndocrineHuman Growth HormoneHumansInfantInfant, NewbornInsulin-Like Growth Factor IReference ValuesHuman Growth HormoneInsulin-Like Growth Factor I

Identifiers

PMID24575549
PMCPMC4146400
OpenAlexW118911653

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.