ReviewFrontiers in human neuroscience2014
Interhemispheric auditory connectivity: structure and function related to auditory verbal hallucinations.
Review in Frontiers in human neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 65 citations in OpenAlex.
- Alterations in interhemispheric gamma-band connectivity are related to the emergence of auditory verbal hallucinations in healthy subjects during NMDA-receptor blockade.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Trial
- N-Acetyl-Aspartate in the dorsolateral prefrontal cortex in men with schizophrenia and auditory verbal hallucinations: A 1.5 T Magnetic Resonance Spectroscopy Study.Scientific reports · 2018Trial
- Dynamic functional connectivity following cochlear implantation: Predicting speech outcomes and exploring brain network dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Common and unique white matter fractional anisotropy patterns in patients with schizophrenia with medication-resistant auditory verbal hallucinations: a retrospective tract-based spatial statistics study.Schizophrenia (Heidelberg, Germany) · 2025Article
- Dichotic turncoats: Lateralization of auditory processing in two dichotic listening tasks using melodies and syllables.PloS one · 2025Article
- Functional Connectivity Between Auditory and Medial Temporal Lobe Networks in Antipsychotic-Naïve Patients With First-Episode Schizophrenia Predicts the Effects of Dopamine Antagonism on Auditory Verbal Hallucinations.Biological psychiatry global open science · 2024Article
- Altered intrinsic neural activity and its molecular analyses in first-episode schizophrenia with auditory verbal hallucinations.Frontiers in neuroscience · 2024Article
- Top-down modulation of dichotic listening affects interhemispheric connectivity: an electroencephalography study.Frontiers in neuroscience · 2024Article
- Abnormal interhemispheric and intrahemispheric functional connectivity dynamics in drug-naïve first-episode schizophrenia patients with auditory verbal hallucinations.Human brain mapping · 2022Article
- Selective Interruption of Auditory Interhemispheric Cross Talk Impairs Discrimination Learning of Frequency-Modulated Tone Direction But Not Gap Detection and Discrimination.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Differences in Cortical Thickness in Schizophrenia Patients With and Without Auditory Verbal Hallucinations.Frontiers in molecular neuroscience · 2022Article
- Auditory hallucinations across the psychosis spectrum: Evidence of dysconnectivity involving cerebellar and temporal lobe regions.NeuroImage. Clinical · 2021Article
- Glutamate- and GABA-Modulated Connectivity in Auditory Hallucinations-A Combined Resting State fMRI and MR Spectroscopy Study.Frontiers in psychiatry · 2021Article
- COMT-Val158Met polymorphism modulates antipsychotic effects on auditory verbal hallucinations and temporal lobe gray matter volumes in healthy individuals-symptom relief accompanied by worrisome volume reductions.Brain imaging and behavior · 2020Article
- Resting state auditory-language cortex connectivity is associated with hallucinations in clinical and biological subtypes of psychotic disorders.NeuroImage. Clinical · 2020Article
- Auditory verbal hallucinations in schizophrenia: current perspectives in brain stimulation treatments.Neuropsychiatric disease and treatment · 2019Review
- Intrinsic 40Hz-phase asymmetries predict tACS effects during conscious auditory perception.PloS one · 2019Article
- The role of functional and structural interhemispheric auditory connectivity for language lateralization - A combined EEG and DTI study.Scientific reports · 2018Article
- The Callosal Relay Model of Interhemispheric Communication: New Evidence from Effective Connectivity Analysis.Brain topography · 2018Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Auditory verbal hallucinations (AVH) are one of the most common and most distressing symptoms of schizophrenia. Despite fundamental research, the underlying neurocognitive and neurobiological mechanisms are still a matter of debate. Previous studies suggested that "hearing voices" is associated with a number of factors including local deficits in the left auditory cortex and a disturbed connectivity of frontal and temporoparietal language-related areas. In addition, it is hypothesized that the interhemispheric pathways connecting right and left auditory cortices might be involved in the pathogenesis of AVH. Findings based on Diffusion-Tensor-Imaging (DTI) measurements revealed a remarkable interindividual variability in size and shape of the interhemispheric auditory pathways. Interestingly, schizophrenia patients suffering from AVH exhibited increased fractional anisotropy (FA) in the interhemispheric fibers than non-hallucinating patients. Thus, higher FA-values indicate an increased severity of AVH. Moreover, a dichotic listening (DL) task showed that the interindividual variability in the interhemispheric auditory pathways was reflected in the behavioral outcome: stronger pathways supported a better information transfer and consequently improved speech perception. This detection indicates a specific structure-function relationship, which seems to be interindividually variable. This review focuses on recent findings concerning the structure-function relationship of the interhemispheric pathways in controls, hallucinating and non-hallucinating schizophrenia patients and concludes that changes in the structural and functional connectivity of auditory areas are involved in the pathophysiology of AVH.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.