Trial reportTheScientificWorldJournal2014
Association of Helicobacter pylori infection with coronary artery disease: is Helicobacter pylori a risk factor?
Trial report in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02317445 (Beijing Tiantan Hospital,Capital Medical University.), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Beijing Tiantan Hospital,Capital Medical University.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Beyond the gut: a comprehensive meta-analysis on Helicobacter pylori infection and cardiovascular complications.Annals of clinical microbiology and antimicrobials · 2025Pooled it
- Article
- Effect of Helicobacter pylori eradication on metabolic profile: an international, multicenter, case-control study.BMC gastroenterology · 2022Article
- Relationship between active Helicobacter pylori infection and risk factors of cardiovascular diseases, a cross-sectional hospital-based study in a Sub-Saharan setting.BMC infectious diseases · 2022Article
- Article
- Bacterial infections are associated with cardiovascular disease in Iran: a meta-analysis.Archives of medical science : AMS · 2019Article
- Levofloxacin-containing triple therapy versus bismuth-based quadruple therapy as regimens for second line anti- Helicobacter pylori.Caspian journal of internal medicine · 2019Article
- Flagellin glycosylation with pseudaminic acid in Campylobacter and Helicobacter: prospects for development of novel therapeutics.Cellular and molecular life sciences : CMLS · 2018Review
- Association ofMedical journal of the Islamic Republic of Iran · 2018Article
- Effect ofJournal of lipids · 2018Article
- Association Between Helicobacter Pylori Infection and Long-term Outcome in Patients with Drug-eluting Stent Implantation.Scientific reports · 2017Article
- Association betweenExperimental and therapeutic medicine · 2017Article
- Article
- Review
- Oxidative DNA damage and oxidized low density lipoprotein in Type II diabetes mellitus among patients with Helicobacter pylori infection.Diabetology & metabolic syndrome · 2016Article
- Helicobacter pylori vs coronary heart disease - searching for connections.World journal of cardiology · 2015Article
- Helicobacter pylori: Does it add to risk of coronary artery disease.World journal of cardiology · 2015Review
- Helicobacter pylori infection and insulin resistance in diabetic and nondiabetic population.TheScientificWorldJournal · 2014Article
- Helicobacter pylori infection prevalence: Is it different in diabetics and nondiabetics?Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHelicobacter pylori (HP) infection is the most common infection in the world and coronary artery disease (CAD) is probably associated with it. The aim of this prospective study was to evaluate the association between HP infection and CAD in suspected patients referred for coronary angiography. The coronary angiography was performed using Judkins method and patients were assigned to participate in CAD positive (>50% luminal diameter stenosis) and negative groups. The serum HP IgG antibody was checked.
resultsPositive and negative CAD groups consisted of 62 and 58 patients, respectively. HP was more prevalent among CAD+ patients, and with increasing the number of coronary arteries with stenosis, the HP seropositivity increased so that 76.3% of patients with multiple vessel diseases (MVD) and 70% of patients with single vessel diseases (SVD) were HP seropositive versus 50% in control group (P = 0.006). Positive CAD was significantly associated with HDL level (P = 0.01) and ESR level (P = 0.006). Also, CAD+ patients had higher CRP levels than controls and it was statistically different between SVD group and controls (P < 0.05).
conclusionHP infection is more prevalent in CAD positive patients and, in case of proving causal relationship, it can be considered as a reversible risk factor for CAD.
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