Evidence map›Paper›PMID 24574754›Full record

ArticleWorld journal of gastroenterology2014

Epidemiological and clinical characteristics of inflammatory bowel diseases in Cairo, Egypt.

Serag Esmat, Mohamed El Nady, Mohamed Elfekki, Yehia Elsherif, Mazen Naga

2 registry-linked trialsAbstract read
In one paragraph

Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04882566 unknown statusnot on this mapstarted 2021, after this paper: background citation

Assessment of Nutritional Knowledge in Patients With Inflammatory Bowel Disease

TypeobservationalSponsorAssiut UniversityRan2021 to 2022Enrolled100ConditionsUlcerative Colitis, Crohn Disease, NutritionArmsPaleolithic Diet
NCT05610956 early_phase1recruitingnot on this mapstarted 2023, after this paper: background citation

Clinical Study to Evaluate the Possible Efficacy and Safety of Empagliflozin in Patients With Ulcerative Colitis

TypeinterventionalSponsorTanta UniversityRan2023 to 2026Enrolled60ConditionsUlcerative ColitisArmsEmpagliflozin, conventional treatment
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Validation of the Arabic version of the composite autonomic symptom score 31 questionnaire in diabetic autonomic neuropathy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Article
  4. Expression profile of serum LncRNAsNon-coding RNA research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Serag EsmatSerag Esmat, Mohamed El Nady, Mazen Naga, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.
Mohamed El NadySerag Esmat, Mohamed El Nady, Mazen Naga, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.
Mohamed ElfekkiSerag Esmat, Mohamed El Nady, Mazen Naga, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.
Yehia ElsherifSerag Esmat, Mohamed El Nady, Mazen Naga, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.
Mazen NagaSerag Esmat, Mohamed El Nady, Mazen Naga, Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the natural history, patterns and clinical characteristics of inflammatory bowel diseases (IBD) in Egypt.

methodsWe designed a case-series study in the gastroenterology centre of the Internal Medicine department of Cairo University, which is a tertiary care referral centre in Egypt. We included all patients in whom the diagnosis of ulcerative colitis (UC) or Crohn's disease (CD) was confirmed by clinical, laboratory, endoscopic, histological and/or radiological criteria over the 15 year period from 1995 to 2009, and we studied their sociodemographic and clinical characteristics. Endoscopic examinations were performed by 2 senior experts. This hospital centre serves patients from Cairo, as well as patients referred from all other parts of Egypt. Our centre received 24156 patients over the described time period for gastro-intestinal consultations and/or interventions.

resultsA total of 157 patients with established IBD were included in this study. Of these, 135 patients were diagnosed with UC (86% of the total), and 22 patients, with CD (14% of the total). The mean ages at diagnosis were 27.3 and 29.7, respectively. Strikingly, we noticed a marked increase in the frequency of both UC and CD diagnoses during the most recent 10 years of the 15 year period studied. Regarding the gender distribution, the male:female ratio was 1:1.15 for UC and 2.6:1 for CD. The mean duration of follow up for patients with UC was 6.2 ± 5.18 years, while the mean duration of follow up for patients with CD was 5.52 ± 2.83 years. For patients with UC we found no correlation between the severity of the disease and the presence of extraintestinal manifestations. Eleven patients had surgical interventions during the studied years: 4 cases of total colectomy and 7 cases of anal surgery.

conclusionWe observed a ratio of 6:1 for UC to CD in our series. The incidence of IBD seems to be rising in Egypt.

Indexed as

AdolescentAdultColectomyColitis, UlcerativeCrohn DiseaseDisease ProgressionEgyptEndoscopy, GastrointestinalFemaleHumansIncidenceMalePrognosisRegistriesRisk FactorsSeverity of Illness IndexEpidemiology of Crohn’s diseaseEpidemiology of inflammatory bowel diseases in EgyptEpidemiology of Ulcerative colitisIncidence of Crohn’s diseaseIncidence of ulcerative colitisinflammatory bowel diseases PrevalenceNatural history of Inflammatory bowel diseases

Identifiers

PMID24574754
PMCPMC3921490

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.