ReviewIndian journal of psychiatry2014
Cannabis and psychosis: Neurobiology.
Review in Indian journal of psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- A review of Indian research on co-occurring cannabis use disorders& psychiatric disorders.The Indian journal of medical research · 2017Pooled it
- Cannabis and tobacco co-use predicts psychosis in clinical high risk cohorts.Nature. Mental health · 2026Article
- The relationship between recreational cannabis use, psychotic-like experiences, and the salience network in adolescent and young adult twins.Psychological medicine · 2025Article
- Cannabis and Tobacco Co-Use Predicts Psychosis in Clinical High Risk Cohorts.medRxiv : the preprint server for health sciences · 2025Article
- Exposotypes in psychotic disorders.Scientific reports · 2025Article
- Cannabis use and dependence among festival attendees: results from the French OCTOPUS survey.BMC public health · 2024Article
- Clinical Variables and Peripheral Biomarkers Associated with Substance-Induced Psychotic Disorder: Differences Related to Alcohol, Cannabis, and Psychostimulant Abuse.Journal of personalized medicine · 2024Article
- The Role of Cannabis in the Development of Psychosis.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2024Review
- Cannabis-Impaired driving: ethical considerations for the primary care practitioner.Annals of medicine · 2023Review
- Terminal type-specific cannabinoid CB1 receptor alterations in patients with schizophrenia: A pilot study.Neurobiology of disease · 2023Article
- Terminal type-specific cannabinoid CB1 receptor alterations in patients with schizophrenia: a pilot study.bioRxiv : the preprint server for biology · 2023Article
- Cell type specific cannabinoid CB1 receptor distribution across the human and non-human primate cortex.Scientific reports · 2022Article
- Levetiracetam-Induced Psychosis in the Setting of Intracranial Cavernomas.Case reports in psychiatry · 2022Article
- Article
- Cannabis and the Developing Brain: Insights into Its Long-Lasting Effects.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Review
- Prolonged Cannabidiol Treatment Effects on Hippocampal Subfield Volumes in Current Cannabis Users.Cannabis and cannabinoid research · 2018Article
- Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation.Translational psychiatry · 2014Article
- The Cannabis Pathway to Non-Affective Psychosis may Reflect Less Neurobiological Vulnerability.Frontiers in psychiatry · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cannabis is a known risk factor for schizophrenia, although the exact neurobiological process through which the effects on psychosis occur is not well-understood. In this review, we attempt to develop and discuss a possible pathway for the development of psychosis. We examine the neurobiological changes due to cannabis to see if these changes are similar to those seen in schizophrenic patients the findings show similarities; however, these mere similarities cannot establish a 'cause-effect' relationship as a number of people with similar changes do not develop schizophrenia. Therefore, the 'transition-to-psychosis' due to cannabis, despite being a strong risk factor, remains uncertain based upon neurobiological changes. It appears that other multiple factors might be involved in these processes which are beyond neurobiological factors. Major advances have been made in understanding the underpinning of marijuana dependence, and the role of the cannabinoid system, which is a major area for targeting medications to treat marijuana withdrawal and dependence, as well as other addictions is of now, it is clear that some of the similarities in the neurobiology of cannabis and schizophrenia may indicate a mechanism for the development of psychosis, but its trajectories are undetermined.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.