Evidence map›Paper›PMID 24574526›Full record

ArticleBMJ case reports2014

DIPNECH presenting on a background of malignant melanoma: new lung nodules are not always what they seem.

Helen Killen

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Helen KillenDepartment of General Medicine, East and North Hertfordshire NHS Trust, Stevenage, Hertfordshire, UK.
East and North Hertfordshire NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coexistence of lung nodules on a CT scan with worsening respiratory symptoms in the context of previous malignant melanoma would usually signify metastatic disease. The cause of the lung nodules in this 69-year-old woman turned out to be diffuse idiopathic neuroendocrine cell hyperplasia (DIPNECH) with tumourlets. DIPNECH is extremely rare, with fewer than 100 cases reported in the literature worldwide. The key to making this diagnosis was that the nodules were not avid on a positron emission tomography-CT scan, as would have been expected in metastatic melanoma. This led to a biopsy diagnosis. At the time of writing, the patient remains symptomatic with stable disease.

Indexed as

AgedBiopsyDiagnosis, DifferentialFemaleHumansHyperplasiaMelanomaMultiple Pulmonary NodulesNeuroendocrine CellsNeuroendocrine TumorsTomography, X-Ray Computed

Identifiers

PMID24574526
PMCPMC3939392
OpenAlexW2102274421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.