Evidence map›Paper›PMID 24574281›Full record

ArticleJournal of clinical microbiology2014

Coinfection of Fusobacterium nucleatum and Actinomyces israelii in mastoiditis diagnosed by next-generation DNA sequencing.

Stephen J Salipante, Daniel R Hoogestraat, April N Abbott, Dhruba J SenGupta, Lisa A Cummings, Susan M Butler-Wu, Karen Stephens, Brad T Cookson, Noah G Hoffman

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  7. Review
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  9. Article
  10. Pathogen detection in suspected spinal infection: metagenomic next-generation sequencing versus culture.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Review
  11. Actinomycosis withBMJ case reports · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Detection of multidrug-resistantFrontiers in public health · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Stephen J SalipanteDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Daniel R Hoogestraat
April N Abbott
Dhruba J SenGupta
Lisa A Cummings
Susan M Butler-Wu
Karen Stephens
Brad T Cookson
Noah G Hoffman
University of Washington · US

Funding

Institute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4M
NCATS NIH HHS UL1 TR000423NCATS NIH HHS UL1TR000423
6 · The paper itself

Abstract

Some bacterial infections involve potentially complex mixtures of species that can now be distinguished using next-generation DNA sequencing. We present a case of mastoiditis where Gram stain, culture, and molecular diagnosis were nondiagnostic or discrepant. Next-generation sequencing implicated coinfection of Fusobacterium nucleatum and Actinomyces israelii, resolving these diagnostic discrepancies.

Indexed as

ActinomycesActinomycosisCoinfectionFusobacterium InfectionsFusobacterium nucleatumHigh-Throughput Nucleotide SequencingHumansMaleMastoiditisMiddle Aged

Identifiers

PMID24574281
PMCPMC3993667
OpenAlexW2024626363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.