Evidence map›Paper›PMID 24574147›Full record

ReviewIntegrated environmental assessment and management2014

The role of biomarkers in the assessment of aquatic ecosystem health.

Sharon E Hook, Evan P Gallagher, Graeme E Batley

Open access · greenAbstract readReview
In one paragraph

Review in Integrated environmental assessment and management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 340 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Molecular response ofCurrent research in toxicology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Toxicogenomics of the Freshwater Oligochaete,International journal of molecular sciences · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Effects of Human Activity on Markers of Oxidative Stress in the Intestine ofInternational journal of molecular sciences · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sharon E HookCSIRO Centre for Environmental Contaminants Research Land and Water, Kirrawee, New South Wales, Australia.
Evan P Gallagher
Graeme E Batley
CSIRO Land and Water · AUUniversity of Washington · US

Funding

WILDLIFE BIOMARKER APPLICATIONS TO REMEDIATION DECISION MAKINGP42ES004696 · NIEHS · UNIVERSITY OF WASHINGTON · PI FURLONG, CLEMENT EUGENE · 1987 to 2021
$51.2M
NIEHS NIH HHS P42 ES004696NIEHS NIH HHS P42ES004696
6 · The paper itself

Abstract

Ensuring the health of aquatic ecosystems and identifying species at risk from the detrimental effects of environmental contaminants can be facilitated by integrating analytical chemical analysis with carefully selected biological endpoints measured in tissues of species of concern. These biological endpoints include molecular, biochemical, and physiological markers (i.e., biomarkers) that when integrated, can clarify issues of contaminant bioavailability, bioaccumulation, and ecological effects while enabling a better understanding of the effects of nonchemical stressors. In the case of contaminant stressors, an understanding of chemical modes of toxicity can be incorporated with diagnostic markers of aquatic animal physiology to help understand the health status of aquatic organisms in the field. Furthermore, new approaches in functional genomics and bioinformatics can help discriminate individual chemicals, or groups of chemicals among complex mixtures that may contribute to adverse biological effects. Although the use of biomarkers is not a new paradigm, such approaches have been underused in the context of ecological risk assessment and natural resource damage assessment. From a regulatory standpoint, these approaches can help better assess the complex effects from coastal development activities to assessing ecosystem integrity pre- and post development or site remediation.

Indexed as

BiomarkersAnimalsBehavior, AnimalEcosystemEnvironmental MonitoringRisk AssessmentWater Pollutants, ChemicalBiomarkersWater Pollutants, ChemicalAssaysFishGene expressionMetalsOilPesticides

Identifiers

PMID24574147
PMCPMC4750648
OpenAlexW2148669164

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.