ArticleAngewandte Chemie (International ed. in English)2014
Chemically orthogonal three-patch microparticles.
Article in Angewandte Chemie (International ed. in English), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Lyotropy as a Design Consideration for Ultra-Small Protein Nanoparticles via Electrohydrodynamic Jetting.Macromolecular rapid communications · 2025Article
- Protein Nanoparticles: Uniting the Power of Proteins with Engineering Design Approaches.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Electrokinetic characterization of synthetic protein nanoparticles.Beilstein journal of nanotechnology · 2020Article
- Compartmentalized Microhelices Prepared via Electrohydrodynamic Cojetting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2018Article
- Janus particles for biological imaging and sensing.The Analyst · 2016Review
- Engineering of nanoparticle size via electrohydrodynamic jetting.Bioengineering & translational medicine · 2016Article
- Dual Release Carriers for Cochlear Delivery.Advanced healthcare materials · 2016Article
- CXCR4-Targeted Nanocarriers for Triple Negative Breast Cancers.Biomacromolecules · 2015Article
- Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders.Advanced materials (Deerfield Beach, Fla.) · 2015Article
- Long-circulating Janus nanoparticles made by electrohydrodynamic co-jetting for systemic drug delivery applications.Journal of drug targeting · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Compared to two-dimensional substrates, only a few methodologies exist for the spatially controlled decoration of three-dimensional objects, such as microparticles. Combining electrohydrodynamic co-jetting with synthetic polymer chemistry, we were able to create two- and three-patch microparticles displaying chemically orthogonal anchor groups on three distinct surface patches of the same particle. This approach takes advantage of a combination of novel chemically orthogonal polylactide-based polymers and their processing by electrohydrodynamic co-jetting to yield unprecedented multifunctional microparticles. Several micropatterned particles were fabricated displaying orthogonal click functionalities. Specifically, we demonstrate novel two- and three-patch particles. Multi-patch particles are highly sought after for their potential to present multiple distinct ligands in a directional manner. This work clearly establishes a viable route towards orthogonal reaction strategies on multivalent micropatterned particles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.