ArticleInternational orthopaedics2014
Opioid use prior to total hip arthroplasty leads to worse clinical outcomes.
Article in International orthopaedics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07784192 (Evaluation of Post-operative Pain Management Methods in Patients Undergoing Total Hip Arthroplasty.), which is not on this map. Cited by 64 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Post-operative Pain Management Methods in Patients Undergoing Total Hip Arthroplasty.
Who cites it
64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 200 citations in OpenAlex.
- [2024 American Academy of Orthopaedic Surgeons (AAOS) Clinical Practice Guideline: Management of Osteoarthritis of the Hip (summary) interpretation].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Guideline
- The functional and psychological impact of delayed hip and knee arthroplasty: a systematic review and meta-analysis of 89,996 patients.Scientific reports · 2024Pooled it
- [Opioids in primary total joint arthroplasty: Interpretation of 2020 AAHKS/ASRA/AAOS/THS/TKS clinical practice guidelines].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021Guideline
- Preoperative opioid use is associated with worse patient outcomes after Total joint arthroplasty: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2019Pooled it
- Variation in patient-reported outcomes after total hip replacement across ten high-volume hospitals in Germany: results from a multicenter, prospective, longitudinal Cohort Study.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Achieving effective and timely quality of care in same-day discharge total hip arthroplasty without compromising patient safety.BMJ open quality · 2026Article
- Preoperative Opioid Use and its Association with Postoperative Complications.Journal of substance use · 2025Article
- The Effect of Lidocaine Splash Block Followed by Suspensory Ligament Massage in Female Dogs Undergoing Ovariohysterectomy: A Prospective Study.Animals : an open access journal from MDPI · 2024Article
- Do modifiable patient factors increase the risk of postoperative complications after total joint arthroplasty?Archives of orthopaedic and trauma surgery · 2024Article
- Interactions and Trends of Interleukins, PAI-1, CRP, and TNF-α in Inflammatory Responses during the Perioperative Period of Joint Arthroplasty: Implications for Pain Management-A Narrative Review.Journal of personalized medicine · 2024Review
- Trends in incidence and average waiting time for arthroplasty from 1998-2021: an observational study of 282,367 patients from the Scottish arthroplasty project.Annals of the Royal College of Surgeons of England · 2024Observational
- Greater Mental Health Burden is Associated With Poor Postoperative Pain Control and Increased Opioid Utilization Following Total Shoulder Arthroplasty.Journal of shoulder and elbow arthroplasty · 2024Article
- Simultaneous selection and inference for varying coefficients with zero regions: a soft-thresholding approach.Biometrics · 2023Article
- Improved perioperative narcotic usage patterns in patients undergoing robotic-assisted compared to manual total hip arthroplasty.Arthroplasty (London, England) · 2023Article
- Females Are More Likely Than Males to Fill an Opioid Prescription in the Year After Anterior Cruciate Ligament Reconstruction.Arthroscopy, sports medicine, and rehabilitation · 2023Article
- Anterior Approach to Hip Arthroplasty with Early Mobilization Key for Reduced Hospital Length of Stay.Medicina (Kaunas, Lithuania) · 2023Article
- Impact of preexisting opioid dependence on morbidity, length of stay, and inpatient cost of urological oncological surgery.World journal of urology · 2023Article
- Modernizing Total Hip Arthroplasty Perioperative Pathways: The Implementation of ERAS-Outpatient Protocol.Journal of clinical medicine · 2022Article
- Analysis of Risk Factors for High-Risk Patients Undergoing Total Joint Arthroplasty.Arthroplasty today · 2022Article
- Opioid use prior to surgery is associated with worse preoperative and postoperative patient reported quality of life and decreased surgical cost effectiveness for symptomatic adult spine deformity; A matched cohort analysis.North American Spine Society journal · 2022Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to compare the clinical outcomes of patients undergoing total hip arthroplasty (THA) who had been using narcotic medications prior to surgery to those who had not used them.
methodsFifty-four patients (62 hips) who had required opioid analgesia for hip pain in the three months prior to THA were compared to a matched group of opioid-naïve patients. Narcotic consumption was converted to a standardized morphine equivalent dose and compared between both groups of patients during their hospital stay, after six weeks, and at final follow-up. Other outcome measures included clinical outcome scores and the proportion of patients remaining on narcotic pain medication at final follow-up.
resultsThe narcotic group required significantly higher total daily opioid doses as inpatients had a longer hospital stay and a higher proportion of patients who remained on opioids at six weeks and at final follow-up. Of the patients who were taking opioids pre-operatively, 81 % were able to wean off opioids at final follow-up. At a mean post-operative follow-up of 58 months (range, 24-258 months), Harris hip scores were lower in the narcotic group, with a mean of 84 compared to 91 points in the matching group. However, in both cohorts, there were significant improvements in Harris hip scores compared to pre-operative outcomes.
conclusionsPatients who use narcotics prior to total hip arthroplasty may be more likely to suffer from opioid-induced hyperalgesia after surgery and have worse clinical outcomes. When possible, efforts should be made to use other modes of analgesia or wean patients from their use prior to total hip arthroplasty.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.