Evidence map›Paper›PMID 24573352›Full record

SynthesisCirculation2014

Temporal trends in ischemic heart disease mortality in 21 world regions, 1980 to 2010: the Global Burden of Disease 2010 study.

Andrew E Moran, Mohammad H Forouzanfar, Gregory A Roth, George A Mensah, Majid Ezzati, Christopher J L Murray, Mohsen Naghavi

Registry-linked trialAbstract readComparative StudySystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Circulation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06062316 (Early Warning Model of Myocardial Remodeling After Acute Myocardial Infarction Based on Multimodal Feature Structure Technology), which is not on this map. Cited by 266 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
266citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06062316 unknown statusnot on this mapstarted 2022, after this paper: background citation

Early Warning Model of Myocardial Remodeling After Acute Myocardial Infarction Based on Multimodal Feature Structure Technology

TypeobservationalSponsorXuanwu Hospital, BeijingRan2022 to 2024Enrolled4,000ConditionsMyocardial Infarction
3 · Its place in the literature

Who cites it

266 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Health-related quality of life in coronary heart disease: a systematic review and meta-analysis mapped against the International Classification of Functioning, Disability and Health.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Pooled it
  10. Trial
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  16. Statins for primary prevention of cardiovascular disease in Germany: benefits and costs.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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  19. Article
  20. Article

206 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Andrew E MoranDivision of General Medicine, Department of Medicine, Columbia University Medical Center, New York, NY (A.E.M.); Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA (M.H.F., G.A.R., C.J.L.M., M.N.); Division of Cardiology, Department of Medicine, University of Washington, Seattle, WA (G.A.R.); Center for Translation Research and Implementation Science (CTRIS), National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (G.A.M.); and MRC-HPA Centre for Environment and Health and Department of Epidemiology and Biostatistics, Imperial College London, London, UK (M.E.).
Mohammad H Forouzanfar
Gregory A Roth
George A Mensah
Majid Ezzati
Christopher J L Murray
Mohsen Naghavi

Funding

Forecasting the Cardiovascular Disease Epidemic in ChinaK08HL089675 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MORAN, ANDREW EDWARD · 2008 to 2012
$650k
Medical Research Council G0801056NHLBI NIH HHS K08 HL089675NHLBI NIH HHS K08 HL089675-01A1
6 · The paper itself

Abstract

backgroundIschemic heart disease (IHD) is the leading cause of death worldwide. The Global Burden of Diseases, Risk Factors and Injuries 2010 Study estimated global and regional IHD mortality from 1980 to 2010. METHODS AND

resultsSources for IHD mortality estimates were country-level surveillance, verbal autopsy, and vital registration data. Regional income, metabolic and nutritional risk factors, and other covariates were estimated from surveys and a systematic review. An estimation and validation process led to an ensemble model of IHD mortality for 21 world regions. Globally, age-standardized IHD mortality has declined since the 1980s, and high-income regions (especially Australasia, Western Europe, and North America) experienced the most remarkable declines. Age-standardized IHD mortality increased in former Soviet Union countries and South Asia in the 1990s and attenuated after 2000. In 2010, Eastern Europe and Central Asia had the highest age-standardized IHD mortality rates. More IHD deaths occurred in South Asia in 2010 than in any other region. On average, IHD deaths in South Asia, North Africa and the Middle East, and sub-Saharan Africa occurred at younger ages in comparison with most other regions.

conclusionsIn most world regions, particularly in high-income regions, age-standardized IHD mortality rates have declined significantly since 1980. High age-standardized IHD mortality in Eastern Europe, Central Asia, and South Asia point to the need to prevent and control established risk factors in those regions and to research the unique behavioral and environmental determinants of higher IHD mortality.

Indexed as

Cost of IllnessAdolescentAdultAgedAged, 80 and overAge FactorsChildChild, PreschoolFemaleGlobal HealthHealth SurveysHumansInfantInfant, NewbornMaleMiddle Agedepidemiologymortalitymyocardial ischemiatrendsworld health

Identifiers

PMID24573352
PMCPMC4181359

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.