Evidence map›Paper›PMID 24573351›Full record

SynthesisCirculation2014

The global burden of ischemic heart disease in 1990 and 2010: the Global Burden of Disease 2010 study.

Andrew E Moran, Mohammad H Forouzanfar, Gregory A Roth, George A Mensah, Majid Ezzati, Abraham Flaxman, Christopher J L Murray, Mohsen Naghavi

Abstract readComparative StudySystematic Review
In one paragraph

Synthesis in Circulation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 315 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
315citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

315 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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255 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Andrew E MoranDivision of General Medicine, Department of Medicine, Columbia University Medical Center, New York, NY (A.E.M.); Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA (M.H.F., G.R., A.F., C.J.L.M., M.N.); Division of Cardiology, Department of Medicine, University of Washington, Seattle, WA (G.R.); Center for Translation Research and Implementation Science (CTRIS), National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (G.A.M.); and MRC-HPA Centre for Environment and Health and Department of Epidemiology and Biostatistics, Imperial College London, London, UK (M.E.).
Mohammad H Forouzanfar
Gregory A Roth
George A Mensah
Majid Ezzati
Abraham Flaxman
Christopher J L Murray
Mohsen Naghavi

Funding

Forecasting the Cardiovascular Disease Epidemic in ChinaK08HL089675 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MORAN, ANDREW EDWARD · 2008 to 2012
$650k
Medical Research Council G0801056NHLBI NIH HHS K08 HL089675NHLBI NIH HHS K08 HL089675-01A1
6 · The paper itself

Abstract

backgroundIschemic heart disease (IHD) burden consists of years of life lost from IHD deaths and years of disability lived with 3 nonfatal IHD sequelae: nonfatal acute myocardial infarction, angina pectoris, and ischemic heart failure. Our aim was to estimate the global and regional burden of IHD in 1990 and 2010. METHODS AND

resultsGlobal and regional estimates of acute myocardial infarction incidence and angina and heart failure prevalence by age, sex, and world region in 1990 and 2010 were estimated based on data from a systematic review and nonlinear mixed-effects meta-regression methods. Age-standardized acute myocardial infarction incidence and angina prevalence decreased globally between 1990 and 2010; ischemic heart failure prevalence increased slightly. The global burden of IHD increased by 29 million disability-adjusted life-years (29% increase) between 1990 and 2010. About 32.4% of the growth in global IHD disability-adjusted life-years between 1990 and 2010 was attributable to aging of the world population, 22.1% was attributable to population growth, and total disability-adjusted life-years were attenuated by a 25.3% decrease in per capita IHD burden (decreased rate). The number of people living with nonfatal IHD increased more than the number of IHD deaths since 1990, but >90% of IHD disability-adjusted life-years in 2010 were attributable to IHD deaths.

conclusionsGlobally, age-standardized acute myocardial infarction incidence and angina prevalence have decreased, and ischemic heart failure prevalence has increased since 1990. Despite decreased age-standardized fatal and nonfatal IHD in most regions since 1990, population growth and aging led to a higher global burden of IHD in 2010.

Indexed as

Cost of IllnessAdolescentAdultAgedAged, 80 and overAge FactorsChildChild, PreschoolFemaleGlobal HealthHumansIncidenceInfantInfant, NewbornMaleMiddle Agedangina pectorisepidemiologyheart failuremyocardial infarctionmyocardial ischemiatrendsworld health

Identifiers

PMID24573351
PMCPMC4181601

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.