ArticleCritical ultrasound journal2014
Prehospital stroke diagnostics based on neurological examination and transcranial ultrasound.
Article in Critical ultrasound journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Practice recommendations for neurovascular ultrasound investigations of acute stroke patients in the setting of the COVID-19 pandemic: an expert consensus from the European Society of Neurosonology and Cerebral Hemodynamics.European journal of neurology · 2020Guideline
- Prehospital stroke scales as screening tools for early identification of stroke and transient ischemic attack.The Cochrane database of systematic reviews · 2019Pooled it
- The role of point of care ultrasound in prehospital critical care: a systematic review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2018Pooled it
- Transcranial ultrasonography in the detection of cerebrovascular accident: a systematic review and bivariate random-effects meta-analysis.Frontiers in neurologyPooled it
- Machine learning enhanced noninvasive transcranial stroke detection using a portable eddy current damping sensor.iScience · 2025Article
- Use of the SONAS Ultrasound Device for the Assessment of Cerebral Perfusion in Acute Ischemic Stroke.Stroke (Hoboken, N.J.) · 2024Article
- The Diagnostic Accuracy of Transcranial Color-Coded Doppler Ultrasound Technique in Stratifying Intracranial Cerebral Artery Stenoses in Cerebrovascular Disease Patients: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Low-Intensity Focused Ultrasound Neuromodulation for Stroke Recovery: A Novel Deep Brain Stimulation Approach for Neurorehabilitation?IEEE open journal of engineering in medicine and biology · 2023Article
- Portable stroke detection devices: a systematic scoping review of prehospital applications.BMC emergency medicine · 2022Article
- Acute Middle Cerebral Artery Occlusion Detection Using Mobile Non-Imaging Brain Perfusion Ultrasound-First Case.Journal of clinical medicine · 2022Article
- A mobile battery-powered brain perfusion ultrasound (BPU) device designed for prehospital stroke diagnosis: correlation to perfusion MRI in healthy volunteers.Neurological research and practice · 2022Article
- Large Vessel Occlusion Stroke Detection in the Prehospital Environment.Current emergency and hospital medicine reports · 2021Article
- Twenty Years of Cerebral Ultrasound Perfusion Imaging-Is the Best yet to Come?Journal of clinical medicine · 2020Review
- Article
- Diagnostic value of transcranial ultrasonography for selecting subjects with large vessel occlusion: a systematic review.The ultrasound journal · 2019Review
- Article
- ABCDE of prehospital ultrasonography: a narrative review.Critical ultrasound journal · 2018Review
- Transcranial Ultrasound in the Helicopter Emergency Medical Services-A Feasibility Study.Journal of neuroimaging : official journal of the American Society of NeuroimagingArticle
- ROLE OF TRANSCRANIAL COLOUR-CODED DUPLEX SONOGRAPHY IN STROKE MANAGEMENT - REVIEW ARTICLE.West African journal of ultrasoundArticle
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTranscranial color-coded sonography (TCCS) has proved to be a fast and reliable tool for the detection of middle cerebral artery (MCA) occlusions in a hospital setting. In this feasibility study on prehospital sonography, our aim was to investigate the accuracy of TCCS for neurovascular emergency diagnostics when performed in a prehospital setting using mobile ultrasound equipment as part of a neurological examination.
methodsFollowing a '911 stroke code' call, stroke neurologists experienced in TCCS rendezvoused with the paramedic team. In patients with suspected stroke, TCCS examination including ultrasound contrast agents was performed. Results were compared with neurovascular imaging (CTA, MRA) and the final discharge diagnosis from standard patient-centered stroke care.
resultsWe enrolled '232 stroke code' patients with follow-up data available in 102 patients with complete TCCS examination. A diagnosis of ischemic stroke was made in 73 cases; 29 patients were identified as 'stroke mimics'. MCA occlusion was diagnosed in ten patients, while internal carotid artery (ICA) occlusion/high-grade stenosis leading to reversal of anterior cerebral artery flow was diagnosed in four patients. The initial working diagnosis 'any stroke' showed a sensitivity of 94% and a specificity of 48%. 'Major MCA or ICA stroke' diagnosed by mobile ultrasound showed an overall sensitivity of 78% and specificity of 98%.
conclusionsThe study demonstrates the feasibility and high diagnostic accuracy of emergency transcranial ultrasound assessment combined with neurological examinations for major ischemic stroke. Future combination with telemedical support, point-of-care analysis of blood serum markers, and probability algorithms of prehospital stroke diagnosis including ultrasound may help to speed up stroke treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.