Evidence map›Paper›PMID 2457159›Full record

ArticleMycopathologia1988

The application of immunoperoxidase staining for the detection of causative fungi in tissue specimens of mycosis I.

K Kobayashi, M Hayama, M Hotchi

Abstract read
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In one paragraph

Article in Mycopathologia, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Acta biochimica et biophysica Sinica · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Candidiasis visualised by proteinase-directed immunofluorescence.Virchows Archiv. A, Pathological anatomy and histopathology · 1991
    Article
  8. Evaluation of a gold-silver staining method for detection and identification of Candida species by light microscopy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1990
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

K KobayashiDepartment of Plastic Surgery, Nagasaki University School of Medicine, Japan.
M Hayama
M Hotchi
Ōtani University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was performed in order to identify the fungi of four species (Aspergillus fumigatus, Fusarium anthophilum, Candida albicans, Cryptococcus neoformans) in formalin-fixed, paraffin-embedded tissue sections by the indirect method of immunoperoxidase staining. Mature albino rabbits were immunized by formalin-killed organisms. The antibodies were prepared by precipitation at a 50% saturation of ammonium sulfate and were checked for cross-reactivities by Ouchterlony's double immunodiffusion and precipitin test. The immunoperoxidase staining was applied to the paraffin-embedded tissue sections of infected mice, human autopsy and biopsy specimens. Although each fungus was stained clearly the cell wall, cross-reactivities appeared among them, however it was possible to identify four fungi by absorption and dilution of the antisera.

Indexed as

Immunoenzyme TechniquesStaining and LabelingAnimalsAspergillosisAspergillus fumigatusCandidiasisCross ReactionsCryptococcosisFusariumImmune SeraImmunodiffusionMiceMycosesRabbitsImmune Sera

Identifiers

PMID2457159
OpenAlexW2040940878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.