ArticleMetabolic syndrome and related disorders2014
Neck circumference is a predictor of metabolic syndrome and obstructive sleep apnea in short-sleeping obese men and women.
Article in Metabolic syndrome and related disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The interplay between the adrenergic system and obesity: a systematic review.International journal of obesity (2005) · 2025Pooled it
- Anthropometric measures and obstructive sleep apnea in children and adolescents: a systematic review of the literature and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- The Effect of Weight-Loss Interventions on Cervical and Chin Subcutaneous Fat Depots; the CENTRAL Randomized Controlled Trial.Nutrients · 2021Trial
- Prevalence and factors associated with uncontrolled systolic blood pressure among treated older adults in Sri Lanka: a nationwide multicenter cross-sectional study.BMC cardiovascular disorders · 2026Article
- Response to Two Standardized Exercise Tests in Dogs with Different Cephalic Biotypes.Veterinary sciences · 2025Article
- Multifactorial relationships among the waist-to-hip ratio, insulin resistance, and obstructive sleep apnea in men: a large-scale cohort study.Nutrition & metabolism · 2025Article
- Development and Validation of a Screening Equation for Obstructive Sleep Apnea.Diagnostics (Basel, Switzerland) · 2025Article
- Sleep apnea screening through a news portal using the STOP-bang questionnaire.Sleep & breathing = Schlaf & Atmung · 2025Article
- Symptom content analysis of OSA questionnaires: time to identify and improve relevance of diversity of OSA symptoms?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Obstructive Sleep Apnea and Stroke: Determining the Mechanisms Behind their Association and Treatment Options.Translational stroke research · 2024Review
- Metabolic Crossroads: Unveiling the Complex Interactions between Obstructive Sleep Apnoea and Metabolic Syndrome.International journal of molecular sciences · 2024Review
- Article
- The Cervical Fat Tissue Volume is a Predictor for Moderate to Severe OSA.Sleep science (Sao Paulo, Brazil) · 2023Article
- Association between neck circumference and diabetes mellitus: a systematic review and meta-analysis.Diabetology & metabolic syndrome · 2023Review
- The Predictive Role of Subcutaneous Adipose Tissue in the Pathogenesis of Obstructive Sleep Apnoea.Life (Basel, Switzerland) · 2022Article
- Anthropometric Measures for the Prognosis of Obstructive Sleep Apnea in Obese.Clinical medicine & research · 2022Article
- Review
- Impact of Hyoid Position, Mandible Body Length and Anthropometric Measurements on Sleep Indices in Patients with Snoring in North Indian Population.Journal of maxillofacial and oral surgery · 2022Article
- Orofacial Myofunctional Therapy in Obstructive Sleep Apnea Syndrome: A Pathophysiological Perspective.Medicina (Kaunas, Lithuania) · 2021Review
- Modeling Risk Factors for Sleep- and Adiposity-Related Cardiometabolic Disease: Protocol for the Short Sleep Undermines Cardiometabolic Health (SLUMBRx) Observational Study.JMIR research protocols · 2021Article
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Authors and funding
10 authors.
Funding
Abstract
backgroundThe constellation of metabolic syndrome, although controversial with regard to its clinical usefulness, is epidemiologically related to increased diabetes risk and cardiovascular mortality. Our goal was to investigate the associations among neck circumference (NC), obstructive sleep apnea syndromes (OSAS), and metabolic syndrome in obese men and women sleeping less than 6.5 hr per night.
methodsThis was a cross-sectional study of obese men and premenopausal obese women sleeping less than 6.5 hr per night. We enrolled 120 individuals (92 women), age 40.5±6.9 years and body mass index (BMI) 38.6±6.5 kg/m(2). Metabolic syndrome severity was assessed by a score and OSAS was defined as a respiratory disturbance index (RDI) ≥5. Metabolic end endocrine parameters were measured, and sleep duration was determined by actigraphy and validated questionnaires.
resultsMetabolic syndrome was found in 41% and OSAS in 58% (28% had both). Subjects with metabolic syndrome were 3 years older and more often Caucasian; they had higher RDI scores, larger NC, more visceral fat, lower serum adiponectin, higher 24-hr urinary norepinephrine (NE) excretion, and lower growth hormone concentrations. A NC of ≥38 cm had a sensitivity of 54% and 58% and a specificity of 70% and 79% in predicting the presence of metabolic syndrome and OSAS, respectively. RDI, adiponectin, and NC accounted for approximately 30% of the variability in the metabolic syndrome score, as estimated by an age-, gender-, and race-corrected multivariate model (R(2)=0.376, P<0.001).
conclusionGreater NC is associated with OSAS and metabolic syndrome in short-sleeping obese men and premenopausal obese women. Addition of NC to the definition of metabolic syndrome should be considered and needs to be validated in future studies.
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