Evidence map›Paper›PMID 24570946›Full record

ReviewHepatobiliary surgery and nutrition2013

Histamine regulation of pancreatitis and pancreatic cancer: a review of recent findings.

Taylor Francis, Allyson Graf, Kyle Hodges, Lindsey Kennedy, Laura Hargrove, Mattie Price, Kate Kearney, Heather Francis

Abstract readReview
In one paragraph

Review in Hepatobiliary surgery and nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Taylor FrancisMedicine, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA.
Allyson GrafResearch, Central Texas Veteran's Health Care System, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA ; Scott & White Digestive Disease Research Center, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA.
Kyle HodgesScott & White Digestive Disease Research Center, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA.
Lindsey KennedyScott & White Digestive Disease Research Center, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA.
Laura HargroveScott & White Digestive Disease Research Center, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA.
Mattie PriceScott & White Digestive Disease Research Center, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA.
Kate KearneyScott & White Digestive Disease Research Center, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA.
Heather FrancisMedicine, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA ; Research, Central Texas Veteran's Health Care System, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA ; Scott & White Digestive Disease Research Center, Scott and White Healthcare, Texas A&M HSC, Temple, TX, USA.
Baylor Scott & White - Central Texas Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pancreas is a dynamic organ that performs a multitude of functions within the body. Diseases that target the pancreas, like pancreatitis and pancreatic cancer, are devastating and often fatal to the suffering patient. Histamine and histamine receptors (H1-H4HRs) have been found to play a critical role in biliary diseases. Accordingly, the biliary tract and the pancreas share similarities with regards to morphological, phenotypical and functional features and disease progression, studies related the role of H1-H4HRs in pancreatic diseases are important. In this review, we have highlighted the role that histamine, histidine decarboxylase (HDC), histamine receptors and mast cells (the main source of histamine in the body) play during both pancreatitis and pancreatic cancer. The objective of the review is to demonstrate that histamine and histamine signaling may be a potential therapeutic avenue towards treatment strategies for pancreatic diseases.

Indexed as

Histaminepancreaspancreatic cancerpancreatitis

Identifiers

PMID24570946
PMCPMC3924685
OpenAlexW1870407395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.