ReviewFrontiers in psychology2014
Sadness might isolate you in a non-smelling world: olfactory perception and depression.
Review in Frontiers in psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 63 citations in OpenAlex.
- Past, Present, and Future of Human Chemical Communication Research.Perspectives on psychological science : a journal of the Association for Psychological Science · 2025Review
- Impact of post-COVID-19 olfactory disorders on quality of life, hedonic experiences and psychiatric dimensions in general population.BMC psychiatry · 2024Article
- Chronic unpredictable mild stress alters odor hedonics and adult olfactory neurogenesis in mice.Frontiers in neuroscience · 2023Article
- What about using sniffin' sticks 12 items test to screen post-COVID-19 olfactory disorders?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Reading the Mind through the Nose: Mentalizing Skills Predict Olfactory Performance.Brain sciences · 2022Article
- International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022Review
- Human olfactory dysfunction: causes and consequences.Cell and tissue research · 2021Review
- Odor Sensitivity Versus Odor Identification in Older US Adults: Associations With Cognition, Age, Gender, and Race.Chemical senses · 2020Article
- Article
- Co-expression network modeling identifies key long non-coding RNA and mRNA modules in altering molecular phenotype to develop stress-induced depression in rats.Translational psychiatry · 2019Article
- Pregnancy reduces the perception of anxiety.Scientific reports · 2017Article
- Brain fingerprints of olfaction: a novel structural method for assessing olfactory cortical networks in health and disease.Scientific reports · 2017Article
- Fancy Citrus, Feel Good: Positive Judgment of Citrus Odor, but Not the Odor Itself, Is Associated with Elevated Mood during Experienced Helplessness.Frontiers in psychology · 2016Article
- Article
- Adult neurogenesis and mental illness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015Review
- Disentangling interoception: insights from focal strokes affecting the perception of external and internal milieus.Frontiers in psychology · 2015Article
- Applied olfactory cognition.Frontiers in psychology · 2014Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Major depressive disorder (MDD) occurs with a high prevalence among mental illnesses. MDD patients experience sadness and hopelessness, with blunted affective reactivity. However, such depressive episodes are also key symptoms in other depressive disorders, like Bipolar Disorder (BPD) or Seasonal Affective Disorder (SAD). Moreover, depressive symptoms can also be found in healthy individuals, but are experienced as less severe or for a shorter duration than in patients. Here, it is aimed to summarize studies investigating odor perception in depression, including depressive states in healthy individuals and patient populations. Odor perception in depression has been assessed with psychophysical methods (olfactory sensitivity, odor identification, and discrimination), and odor ratings (intensity, emotional valence, familiarity). In addition, some studies investigated affective reactions to odors, and physiological and anatomical correlates of odor perception in depression. The summary reveals that MDD is associated with reduced olfactory sensitivity. However, odor identification and discrimination scores seem to be unaffected by depression. The reduced olfactory sensitivity might be associated with a reduced ability to encode olfactory information and a reduced volume of the olfactory bulb. While similar processes seem to occur in healthy individuals experiencing depressive states, they have not been observed in BPD or SAD patients. However, in order to conclude that the reduced olfactory sensitivity is directly linked to depression, it is suggested that studies should implement control measures of cognitive performances or perceptual abilities in other stimulus modalities. It is concluded that the reduced olfactory performance in MDD patients seems to be disorder-, modality-, and test-specific, and that the application of an appropriate olfactory and cognitive test-battery might be highly useful in the differential diagnosis of MDD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.