Evidence map›Paper›PMID 24570593›Full record

ReviewOncoTargets and therapy2014

Recent advances in the ARID family: focusing on roles in human cancer.

Chen Lin, Wei Song, Xinyu Bi, Jianjun Zhao, Zhen Huang, Zhiyu Li, Jianguo Zhou, Jianqiang Cai, Hong Zhao

Abstract readReview
In one paragraph

Review in OncoTargets and therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
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  12. Machine Learning for Detecting and Analyzing Chromoanagenesis Events.Methods in molecular biology (Clifton, N.J.) · 2025
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  15. Article
  16. CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities inInternational journal of molecular sciences · 2023
    Article
  17. Article
  18. IKAROS in Acute Leukemia: A Positive Influencer or a Mean Hater?International journal of molecular sciences · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chen LinDepartment of Abdominal Surgical Oncology, Cancer Hospital, Beijing, People's Republic of China.
Wei SongNational Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Xinyu BiDepartment of Abdominal Surgical Oncology, Cancer Hospital, Beijing, People's Republic of China.
Jianjun ZhaoDepartment of Abdominal Surgical Oncology, Cancer Hospital, Beijing, People's Republic of China.
Zhen HuangDepartment of Abdominal Surgical Oncology, Cancer Hospital, Beijing, People's Republic of China.
Zhiyu LiDepartment of Abdominal Surgical Oncology, Cancer Hospital, Beijing, People's Republic of China.
Jianguo ZhouDepartment of Abdominal Surgical Oncology, Cancer Hospital, Beijing, People's Republic of China.
Jianqiang CaiDepartment of Abdominal Surgical Oncology, Cancer Hospital, Beijing, People's Republic of China.
Hong ZhaoDepartment of Abdominal Surgical Oncology, Cancer Hospital, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human AT-rich interaction domain (ARID) family contains seven subfamilies and 15 members characterized by having an ARID. Members of the ARID family have the ability to regulate transcription and are involved in cell differentiation and proliferation. Accumulating evidence suggests that ARID family members are involved in cancer-related signaling pathways, highly mutated or differentially expressed in tumor tissues, and act as predictive factors for cancer prognosis or therapeutic outcome. Here we review the molecular biology and clinical studies concerned with the role played by the ARID family in cancer. This may contribute to our understanding of the initiation and progression of cancer from a novel point of view, as well as providing potential targets for cancer therapy.

Indexed as

AT-rich interaction domaincancer-related signaling pathwayhuman cancerpotential targetstherapy

Identifiers

PMID24570593
PMCPMC3933769

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.