ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2014
Related factors of dental caries and molar incisor hypomineralisation in a group of children with cystic fibrosis.
Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- The prevalence of developmental defects of enamel in people with cystic fibrosis: a systematic review.BMC oral health · 2024Pooled it
- An update of the aetiological factors involved in molar incisor hypomineralisation (MIH): a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2022Pooled it
- Association between respiratory diseases and molar-incisor hypomineralization: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Cystic fibrosis and its impact on the oral cavity and dental treatments - a scoping review.Clinical oral investigations · 2026Article
- Ano1 Antisense Therapy Improves Enamel Properties in Molars but not Amelogenesis in a Murine Model of Cystic Fibrosis.Calcified tissue international · 2026Article
- RIG-I and MDA5 Expression Levels in the Inflamed Pulp Tissues of Dental Caries.Advanced biomedical research · 2025Article
- Oral health and related outcomes in children and adolescents with cystic fibrosis: a scoping review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- Article
- Oral care considerations for people with cystic fibrosis: a cross-sectional qualitative study.BDJ open · 2023Article
- Oral Hygiene and Periodontal Treatment Needs in Adult Patients with Cystic Fibrosis (CF).Healthcare (Basel, Switzerland) · 2022Article
- Associations between dental caries and systemic diseases: a scoping review.BMC oral health · 2021Article
- Salivary Biomarkers and Oral Microbial Load in Relation to the Dental Status of Adults with Cystic Fibrosis.Microorganisms · 2019Article
- Oral health of cystic fibrosis patients at a north american center: A pilot study.Medicina oral, patologia oral y cirugia bucal · 2019Article
- Toothbrushes may convey bacteria to the cystic fibrosis lower airways.Journal of oral microbiology · 2019Article
- DENTAL ENAMEL FORMATION AND IMPLICATIONS FOR ORAL HEALTH AND DISEASE.Physiological reviews · 2017Review
- Unstimulated Saliva-Related Caries Risk Factors in Individuals with Cystic Fibrosis: A Cross-Sectional Analysis of Unstimulated Salivary Flow, pH, and Buffering Capacity.Caries research · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate dental caries and molar incisor hypomineralisation (MIH)-related factors such as treatment, diet, brushing and salivary factors in children with cystic fibrosis (CF) compared with healthy peers. STUDY
designA cohort study was performed.
methodsThis study was performed on 30 CF children comprising patients at the Faculty of Medicine and 30 control children recruited from the Dental School. Salivary factors, dental caries, MIH, daily diet, brushing habits were analysed. Statistical analysis was calculated by SPSS for Windows.
resultsDecay missing filled teeth (DMF-T) score was 4.6 ± 4.0 in CF and 7.7 ± 2.7 in control (p = 0.001). 43% of CF children with MIH were found to use antibiotics, but no significant difference in the caries experience was found with antibiotic usage (p > 0.05). DMF-T of CF adolescents (23%) who use Tobramycin was 7 ± 3.5. DMF-T of CF children (20%) who take other antibiotics was 2.5 ± 3.5, but no statistical difference was found (p = 0.054). Saliva pH, salivary flow rate, and buffering capacity were not found statistically significant (p > 0.05). STATISTICS: Percentage arithmetic mean value, standard deviation, independent sample t test, Fisher's exact test, Chi-square test and Mann-Whitney U test were used, while a p value of <0.05 was considered statistically significant.
conclusionsMedication and diet could be considered as a risk factor for dental caries and factors such as salivary pH, good oral hygiene could play a protective role for oral health CF children. MIH frequency and lower caries experience seen in CF children could be due to salivary factors or pharmacological treatment they take. The multidisciplinary approach team would be advantageous in the management of children with CF and oral health should be under control during early years of life by paediatric dentists.
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