ArticleHeredity2014
Quantitative trait loci from the host genetic background modulate the durability of a resistance gene: a rational basis for sustainable resistance breeding in plants.
Article in Heredity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Role of the Genetic Background in Resistance to Plant Viruses.International journal of molecular sciences · 2018Pooled it
- Specialized Metabolic Reprogramming in Plant Immunity: Biosynthetic Networks, Spatiotemporal Regulation, and Quantitative Defense.Plants (Basel, Switzerland) · 2026Review
- The replicative fitness and virulence of potato virus Y evolve differently in pepper lines with different levels of resistance and tolerance.The Journal of general virology · 2026Article
- Arabidopsis eIF4E1 protects the translational machinery during TuMV infection and restricts virus accumulation.PLoS pathogens · 2023Article
- Plant eIF4E isoforms as factors of susceptibility and resistance to potyviruses.Frontiers in plant science · 2023Review
- Concurrent evolution of resistance and tolerance to potato virus Y in Capsicum annuum revealed by genome-wide association.Molecular plant pathology · 2022Article
- Genome-wide association study for resistance toFrontiers in plant science · 2022Article
- Article
- When a knockout is an Achilles' heel: Resistance to one potyvirus species triggers hypersusceptibility to another one in Arabidopsis thaliana.Molecular plant pathology · 2021Article
- QTL Mapping for Resistance to Cankers Induced byPathogens (Basel, Switzerland) · 2020Article
- Overview of Biotic Stresses in Pepper (International journal of molecular sciences · 2020Review
- Genome-wide association mapping of QTLs implied in potato virus Y population sizes in pepper: evidence for widespread resistance QTL pyramiding.Molecular plant pathology · 2020Article
- Impact of genetic drift, selection and accumulation level on virus adaptation to its host plants.Molecular plant pathology · 2018Article
- Identification ofG3 (Bethesda, Md.) · 2017Article
- Quantitative Resistance to Plant Pathogens in Pyramiding Strategies for Durable Crop Protection.Frontiers in plant science · 2017Review
- Diversity of genetic backgrounds modulating the durability of a major resistance gene. Analysis of a core collection of pepper landraces resistant to Potato virus Y.Molecular plant pathology · 2016Article
- Plant Genetic Background Increasing the Efficiency and Durability of Major Resistance Genes to Root-knot Nematodes Can Be Resolved into a Few Resistance QTLs.Frontiers in plant science · 2016Article
- Pyramiding, alternating or mixing: comparative performances of deployment strategies of nematode resistance genes to promote plant resistance efficiency and durability.BMC plant biology · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The combination of major resistance genes with quantitative resistance factors is hypothesized as a promising breeding strategy to preserve the durability of resistant cultivar, as recently observed in different pathosystems. Using the pepper (Capsicum annuum)/Potato virus Y (PVY, genus Potyvirus) pathosystem, we aimed at identifying plant genetic factors directly affecting the frequency of virus adaptation to the major resistance gene pvr2(3) and at comparing them with genetic factors affecting quantitative resistance. The resistance breakdown frequency was a highly heritable trait (h(2)=0.87). Four loci including additive quantitative trait loci (QTLs) and epistatic interactions explained together 70% of the variance of pvr2(3) breakdown frequency. Three of the four QTLs controlling pvr2(3) breakdown frequency were also involved in quantitative resistance, strongly suggesting that QTLs controlling quantitative resistance have a pleiotropic effect on the durability of the major resistance gene. With the first mapping of QTLs directly affecting resistance durability, this study provides a rationale for sustainable resistance breeding. Surprisingly, a genetic trade-off was observed between the durability of PVY resistance controlled by pvr2(3) and the spectrum of the resistance against different potyviruses. This trade-off seemed to have been resolved by the combination of minor-effect durability QTLs under long-term farmer selection.
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