ReviewCurrent opinion in allergy and clinical immunology2014
Early-life viral infections and the development of asthma: a target for asthma prevention?
Review in Current opinion in allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Epidemiology of moderate-to-severe respiratory syncytial virus infections in children in subtropical Okinawa, Japan: a 4-year retrospective study.Tropical medicine and health · 2025Article
- Asthma, atopy and lung function in young adults after hospitalisation for bronchiolitis in infancy: impact of virus and sex.BMJ open respiratory research · 2022Article
- Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics.International journal of environmental research and public health · 2021Review
- Early Life Factors Associated with Preschool Wheezing in Preterm Infants.Children (Basel, Switzerland) · 2021Article
- Prenatal pesticide exposure and respiratory health outcomes in the first year of life: Results from the infants' Environmental Health (ISA) study.International journal of hygiene and environmental health · 2020Article
- Effect of acute respiratory infections in infancy on pulmonary function test at 3 years of age: a prospective birth cohort study.BMJ open respiratory research · 2020Article
- TLR Activation Alters Bone Marrow-Derived Macrophage Differentiation.Journal of innate immunity · 2019Article
- Healthier without healthcare? The paradox of the common cold.Respiratory research · 2018Article
- Viral Respiratory Infections in the Neonatal Intensive Care Unit-A Review.Frontiers in microbiology · 2018Review
- Effects of Allergic Sensitization on Antiviral Immunity: Allergen, Virus, and Host Cell Mechanisms.Current allergy and asthma reports · 2017Review
- Influence of meteorological conditions on RSV infection in Portugal.International journal of biometeorology · 2016Article
- Review of the clinical significance of respiratory virus infections in newborn infants.Acta paediatrica (Oslo, Norway : 1992) · 2016Review
- Early-life respiratory infections and asthma development: role in disease pathogenesis and potential targets for disease prevention.Current opinion in allergy and clinical immunology · 2016Review
- The contributions of allergic sensitization and respiratory pathogens to asthma inception.The Journal of allergy and clinical immunology · 2016Review
- Genetic polymorphisms and risk of recurrent wheezing in pediatric age.BMC pulmonary medicine · 2014Article
- Inhaled interferon: a novel treatment for virus-induced asthma?American journal of respiratory and critical care medicine · 2014Article
- Wheezing exacerbations in early childhood: evaluation, treatment, and recent advances relevant to the genesis of asthma.The journal of allergy and clinical immunology. In practiceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purpose of reviewTo discuss the recent insights into the relationships between viral respiratory infections and asthma inception in the context of a long-term goal of moving toward prevention strategies for childhood asthma. RECENT
findingsThere is strong evidence for respiratory syncytial virus and human rhinovirus wheezing illnesses as important risk factors for asthma inception. The mechanisms underlying these relationships have been an intense area of study. Novel approaches for the prevention of virus infections and/or lessening the severity of associated illnesses are at various stages of development, and are important potential tools in efforts aimed at primary and secondary prevention of asthma. SUMMARY: Viral respiratory infections in early life are a major source of morbidity and are critical in the development of asthma. Mechanisms by which these infections lead to asthma inception in susceptible individuals are emerging. Further, there are promising potential interventions currently available that should be tested in clinical trials. The goal of prevention of disease inception is clearly on the horizon.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.