Trial reportJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2014
Office probing for treatment of nasolacrimal duct obstruction in infants.
Trial report in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial Comparing Immediate Probing in an Office Setting With Deferred Probing in a Facility Setting for Treatment of Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old
Case Control Study of the Factors That Affected the Outcome of Treatment of Congenital Nasolacrimal Duct Obstruction
Who cites it
17 citing papers in PubMed, 47 citations in OpenAlex.
- Congenital nasolacrimal duct obstruction outcomes.Paediatrics & child health · 2026Article
- Trochlear Nerve Palsy: A Systematic Review of Etiologies and Diagnostic Insights.Diagnostics (Basel, Switzerland) · 2025Review
- Congenital nasolacrimal duct obstruction: clinical guideline.Japanese journal of ophthalmology · 2024Article
- Assessment of Office-Based Probing with Dacryoendoscopy for Treatment of Congenital Nasolacrimal Duct Obstruction: A Retrospective Study.Journal of clinical medicine · 2023Article
- Trends in congenital nasolacrimal duct obstruction surgical procedures in the United States from 2003 to 2016.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2021Article
- Management of congenital nasolacrimal duct obstruction: results of a national survey of paediatric and oculoplastic ophthalmologists.Eye (London, England) · 2021Article
- Efficacy and Safety of Inhalation Sedation during Office Probing for Congenital Nasolacrimal Duct Obstruction.Journal of clinical medicine · 2021Article
- Dacryoendoscopy-assisted incision of Hasner's valve under nasoendoscopy for membranous congenital nasolacrimal duct obstruction after probing failure: a retrospective study.BMC ophthalmology · 2021Article
- Success rates of probing for congenital nasolacrimal duct obstruction at various ages.BMC ophthalmology · 2020Article
- Congenital Nasolacrimal Duct Obstruction (CNLDO): A Review.Diseases (Basel, Switzerland) · 2018Review
- Pediatric nasolacrimal duct obstruction-benefit of a combined therapeutic approach.World journal of pediatrics : WJP · 2017Article
- Congenital nasolacrimal duct obstruction: Should we continue lacrimal massage till 1 year or perform an office probing at 6 months? A clinical decision analysis approach.Indian journal of ophthalmology · 2017Article
- Success rates of dacryoendoscopy-guided probing for recalcitrant congenital nasolacrimal duct obstruction.Japanese journal of ophthalmology · 2016Article
- Bicanalicular versus monocanalicular intubation after failed probing in congenital nasolacrimal duct obstruction.International journal of ophthalmology · 2016Article
- [Treatment of congenital lacrimal duct obstruction: A prospective clinical cohort study].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2015Article
- Dacryoscintigraphic findings in the children with tearing.Korean journal of ophthalmology : KJO · 2015Article
- Navigating congenital nasolacrimal duct obstruction: A practical guide to stepwise management.Oman journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
23 authors at 6 institutions in 1 country.
Funding
Abstract
purposeTo determine whether demographic or clinical factors are associated with the outcome of office-based nasolacrimal duct probing for the treatment of congenital nasolacrimal duct obstruction (NLDO).
methodsIn two multicenter prospective studies, 384 eyes of 304 children aged 6 to <15 months with NLDO underwent a nasolacrimal duct probing performed in the office using topical anesthesia. Treatment success, defined as no clinical signs of NLDO (epiphora, increased tear lake, or mucous discharge) and no reoperation, was assessed 1 month after probing in one study and 6 months after probing in the other study. Data from both studies were pooled to evaluate associations between baseline characteristics and treatment success.
resultsOffice probing was successful in 75% of eyes overall (95% CI, 70%-80%). The procedure was less successful in eyes of children with bilateral NLDO compared with unilateral NLDO (63% vs 80%; relative risk = 0.78 [95% CI, 0.66-0.92]) and in eyes that had 2 or 3 clinical signs of NLDO compared with one (71% vs 83%; relative risk = 0.88 [95% CI, 0.81-0.96]). Treatment success did not appear to be related to age, specific clinical signs of NLDO, prior treatment, or research study.
conclusionsPerforming nasolacrimal duct probing in the office successfully treats NLDO in the majority of cases in children aged 6 to <15 months. The success rate is lower with bilateral disease or when more than one clinical sign of NLDO is present.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.