Evidence map›Paper›PMID 24568208›Full record

ArticleCOPD2014

Occupational risk factors for COPD phenotypes in the Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study.

Brent Doney, Eva Hnizdo, Monica Graziani, Greg Kullman, Cecil Burchfiel, Sherry Baron, Kaori Fujishiro, Paul Enright, John L Hankinson, Karen Hinckley Stukovsky and 3 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in COPD, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. The Effect of Fire Smoke Exposure on Firefighters' Lung Function: A Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  2. Occupational COPD and job exposure matrices: a systematic review and meta-analysis.International journal of chronic obstructive pulmonary disease · 2017
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. COPD in Smoking and Non-Smoking Community Members Exposed to the World Trade Center Dust and Fumes.International journal of environmental research and public health · 2022
    Article
  9. Chronic productive cough and inhalant occupational exposure-a study of the general population.International archives of occupational and environmental health · 2021
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Occupational Exposure to Vapor-Gas, Dust, and Fumes in a Cohort of Rural Adults in Iowa Compared with a Cohort of Urban Adults.Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002) · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Brent Doney1National Institute for Occupational Safety and Health (preferred mailing address)Division of Respiratory Disease Studies, Surveillance Branch 1095 Willowdale Road Morgantown , West Virginia, 26505 USA and West Virginia University School of Public Health PO Box 9190 Morgantown, WV, 26506 USA , Email: bdoney@cdc.gov , Fax: (304) 285-6111.
Eva Hnizdo
Monica Graziani
Greg Kullman
Cecil Burchfiel
Sherry Baron
Kaori Fujishiro
Paul Enright
John L Hankinson
Karen Hinckley Stukovsky
Christopher J Martin
Kathleen M Donohue
R Graham Barr
National Institute for Occupational Safety and Health · USColumbia University · USUniversity of Arizona · USUniversity of Washington · USWest Virginia University · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Ami R Zota · 1998 to 2026
$44.7M
Pulmonary microvascular perfusion in the Multi-Ethnic Study of AtherosclerosisR01HL077612 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2004 to 2026
$18.8M
Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary Disease (COPD)R01HL093081 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2008 to 2026
$17.2M
Biostatistics, Epidemiologic & Bioinformatic Training in Environmental HealthT32ES015459 · NIEHS · UNIVERSITY OF WASHINGTON · PI June T. Spector · 2009 to 2026
$10.6M
Fish Oil Intake, Biomarkers and Change in Lung FunctionR01HL075476 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARR, R GRAHAM · 2004 to 2008
$2.8M
Adjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095165 · HC · WAKE FOREST UNIVERSITY · PI BURKE, GREGORY L · 1999 to 2001
$616k
Enhancing immune reconstitution after implantation of postnatal allogeneic thymusR21HL095165 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CROOKS, GAY M · 2008 to 2009
$440k
SUBCLINICAL CARDIOVASCULAR DISEASE COORDINATING CENTER-N01HC95159-268095159N01HC095159 · HC · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 1999 to 2006
$304k
Adjunctive Use of Apyrase to Fibrinolytic TherapyR43HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2009 to 2009
$226k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--EBCT READINGN01HC095169 · HC · LA BIOMED RES INST/ HARBOR UCLA MED CTR · PI DETRANO, ROBERT · 1999 to 2001
$124k
NHLBI NIH HHS HL075476NHLBI NIH HHS HL077612NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095169NHLBI NIH HHS N01-HC-95159NHLBI NIH HHS N01-HC-95165NHLBI NIH HHS N01-HC-95169NHLBI NIH HHS R01 HL075476NHLBI NIH HHS R01 HL077612NHLBI NIH HHS R01 HL093081NIEHS NIH HHS P30 ES009089NIEHS NIH HHS T32 ES015459PHS HHS FY08 CRN SLB8
6 · The paper itself

Abstract

introductionThe contribution of occupational exposure to the risk of chronic obstructive pulmonary disease COPD in population-based studies is of interest. We compared the performance of self-reported exposure to a newly developed JEM in exposure-response evaluation.

methodsWe used cross-sectional data from Multi-Ethnic Study of Atherosclerosis (MESA), a population-based sample of 45-84 year olds free of clinical cardiovascular disease at baseline. MESA ascertained the most recent job and employment, and the MESA Lung Study measured spirometry, and occupational exposures for 3686 participants. Associations between health outcomes (spirometry defined airflow limitation and Medical Research Council-defined chronic bronchitis) and occupational exposure [self-reported occupational exposure to vapor-gas, dust, or fumes (VGDF), severity of exposure, and a job-exposure matrix (JEM)-derived score] were evaluated using logistic regression models adjusted for non-occupational risk factors.

resultsThe prevalence of airflow limitation was associated with self-reported exposure to vapor-gas (OR 2.6, 95%CI 1.1-2.3), severity of VGDF exposure (P-trend < 0.01), and JEM dust exposure (OR 2.4, 95%CI 1.1-5.0), and with organic dust exposure in females; these associations were generally of greater magnitude among never smokers. The prevalence of chronic bronchitis and wheeze was associated with exposure to VGDF. The association between airflow limitation and the combined effect of smoking and VGDF exposure showed an increasing trend. Self-reported vapor-gas, dust, fumes, years and severity of exposure were associated with increased prevalence of chronic bronchitis and wheeze (P < 0.001).

conclusionsAirflow limitation was associated with self-reported VGDF exposure, its severity, and JEM-ascertained dust exposure in smokers and never-smokers in this multiethnic study.

Indexed as

Self ReportAgedAged, 80 and overAtherosclerosisBronchitis, ChronicCross-Sectional StudiesDustEthnicityFemaleForced Expiratory VolumeGasesHumansMaleMiddle AgedOccupational ExposurePhenotypeDustGasesairflow obstructiondustfumesgasjob exposure matrixSpirometry

Identifiers

PMID24568208
PMCPMC4096066
OpenAlexW1993397887

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.