ArticleEvolutionary applications2014
Genomic selection for recovery of original genetic background from hybrids of endangered and common breeds.
Article in Evolutionary applications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- The paradoxical extinction: Exploring signatures of assortative mating as a possible mechanism that maintains canonical Red Wolf genetic ancestry in the American Gulf Coast canids.The Journal of heredity · 2026Article
- How admixed captive breeding populations could be rescued using local ancestry information.Molecular ecology · 2025Article
- Genetic diversity and family groups detected in a coyote population with red wolf ancestry on Galveston Island, Texas.BMC ecology and evolution · 2022Article
- Benefit of Introgression Depends on Level of Genetic Trait Variation in Cereal Breeding Programmes.Frontiers in plant science · 2022Article
- Opportunities of Genomics for the Use of Semen Cryo-Conserved in Gene Banks.Frontiers in genetics · 2022Review
- Distinguishing the victim from the threat: SNP-based methods reveal the extent of introgressive hybridization between wildcats and domestic cats in Scotland and inform future in situ and ex situ management options for species restoration.Evolutionary applications · 2019Article
- Key Genetic Parameters for Population Management.Frontiers in genetics · 2019Article
- Rediscovery of Red Wolf Ghost Alleles in a Canid Population Along the American Gulf Coast.Genes · 2018Article
- Hybridization and extinction.Evolutionary applications · 2016Review
- What can livestock breeders learn from conservation genetics and vice versa?Frontiers in genetics · 2015Review
- Comparative genomics for biodiversity conservation.Computational and structural biotechnology journal · 2015Review
- Genomic analysis for managing small and endangered populations: a case study in Tyrol Grey cattle.Frontiers in genetics · 2015Article
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3 authors.
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Abstract
Critically endangered breeds and populations are often crossed with more common breeds or subspecies. This results in genetic admixture that can be undesirable when it challenges the genetic integrity of wild and domestic populations, causing a loss in special characteristics or unique genetic material and ultimately extinction. Here, we present two genomic selection strategies, using genome-wide DNA markers, to recover the genomic content of the original endangered population from admixtures. Each strategy relies on the estimation of the proportion of nonintrogressed genome in individuals based on a different method: either genomic prediction or identification of breed-specific haplotypes. Then, breeding programs that remove introgressed genomic information can be designed. To test these strategies, we used empirical 50K SNP array data from two pure sheep breeds, Merino (used as target breed), Poll Dorset and an existing admixed population of both breeds. Sheep populations with varying degrees of introgression and admixture were simulated starting from these real genotypes. Both strategies were capable of identifying segment origin, and both removed up to the 100% of the Poll Dorset segments. While the selection process led to substantial inbreeding, we controlled it by imposing a minimum number of individuals contributing to the next generation.
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