ArticleFrontiers in genetics2014
Assessing the quality of studies supporting genetic susceptibility and outcomes of ARDS.
Article in Frontiers in genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ethnic and age-specific acute lung injury/acute respiratory distress syndrome risk associated with angiotensin-converting enzyme insertion/deletion polymorphisms, implications for COVID-19: A meta-analysis.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021Pooled it
- Genetic Determinants of the Acute Respiratory Distress Syndrome.Journal of clinical medicine · 2023Review
- Association of HLA-DPA1 polymorphism with prolonged mechanical ventilation in patients undergoing liver transplantation.Korean journal of anesthesiology · 2022Article
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- Comparative Study of Acute Lung Injury in COVID-19 and Non-COVID-19 Patients.Frontiers in medicine · 2021Article
- Genomics and the Acute Respiratory Distress Syndrome: Current and Future Directions.International journal of molecular sciences · 2019Review
- Relationship between β-defensin-1 gene polymorphism and susceptibility and prognosis of acute respiratory distress syndrome.Medicine · 2019Article
- A vascular endothelial growth factor receptor gene variant is associated with susceptibility to acute respiratory distress syndrome.Intensive care medicine experimental · 2018Article
- Biomarkers for the acute respiratory distress syndrome: how to make the diagnosis more precise.Annals of translational medicine · 2017Review
- Acute respiratory distress syndrome.Lancet (London, England) · 2016Review
- Happy 50th birthday ARDS!Intensive care medicine · 2016Article
- Common variants of NFE2L2 gene predisposes to acute respiratory distress syndrome in patients with severe sepsis.Critical care (London, England) · 2015Article
- Lung Transcriptomics during Protective Ventilatory Support in Sepsis-Induced Acute Lung Injury.PloS one · 2015Article
- Beyond single-nucleotide polymorphisms: genetics, genomics, and other 'omic approaches to acute respiratory distress syndrome.Clinics in chest medicine · 2014Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The acute respiratory distress syndrome (ARDS) is a severe inflammatory disease manifested as a result of pulmonary and systemic responses to several insults. It is now well accepted that genetic variation influences these responses. However, little is known about the genes that are responsible for patient susceptibility and outcome of ARDS. Methodological flaws are still abundant among genetic association studies with ARDS and here, we aimed to highlight the quality criteria where the standards have not been reached, to expose the associated genes to facilitate replication attempts, and to provide quick-reference guidance for future studies. We conducted a PubMed search from January 2008 to September 2012 for original articles. Studies were considered if a statistically significant association was declared with either susceptibility or outcomes of all-cause ARDS. Fourteen criteria were used for evaluation and results were compared to those from a previous quality assessment report. Significant improvements affecting study design and statistical analysis were detected. However, major issues such as adjustments for the underlying population stratification and replication studies remain poorly addressed.
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