Evidence map›Paper›PMID 24567576›Full record

Observational studyThe British journal of general practice : the journal of the Royal College of General Practitioners2014

Use of alarm features in referral of febrile children to the emergency department: an observational study.

Yvette van Ierland, Gijs Elshout, Henriëtte A Moll, Ruud G Nijman, Yvonne Vergouwe, Johan van der Lei, Marjolein Y Berger, Rianne Oostenbrink

Abstract readObservational Study
In one paragraph

Observational study in The British journal of general practice : the journal of the Royal College of General Practitioners, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Identifying serious bacterial illness in children: is it time to show the red card to NICE's red flags?The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yvette van IerlandDepartment of General Paediatrics, ErasmusMC - Sophia Children's Hospital, Rotterdam, The Netherlands.
Gijs Elshout
Henriëtte A Moll
Ruud G Nijman
Yvonne Vergouwe
Johan van der Lei
Marjolein Y Berger
Rianne Oostenbrink

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnostic value of alarm features of serious infections in low prevalence settings is unclear.

aimTo explore to what extent alarm features play a role in referral to the emergency department (ED) by GPs who face a febrile child during out-of-hours care. DESIGN AND

settingObservational study using semi-structured, routine clinical practice data of febrile children (<16 years) presenting to GP out-of-hours care.

methodLogistic regression analyses were performed to assess the association between alarm features of serious infections (selected from two guidelines and one systematic review) and referral to the ED. Adherence to the guideline was explored by a 2×2 contingency table.

resultsIn total 794 (8.1%) of 9794 eligible patients were referred to the ED. Alarm signs most strongly associated with referral were 'age <1 month', 'decreased consciousness', 'meningeal irritation', and 'signs of dehydration'. Nineteen percent of 3424 children with a positive referral indication according to the guideline were referred to the ED. The majority of those not referred had only one or two alarm features present. A negative referral indication was adhered to for the majority of children. Still, in 20% of referred children, alarm features were absent.

conclusionIn contrast to guidance, GPs working in primary out-of-hours care seem more conservative in referring febrile children to the ED, especially if only one or two alarm features of serious infection are present. In addition, in 20% of referred children, alarm features were absent, which suggests that other factors may be important in decisions about referral of febrile children to the hospital ED.

Indexed as

AdolescentAfter-Hours CareChildChild, PreschoolEmergency Service, HospitalFeverGeneral PracticeGuideline AdherenceHumansInfantInfant, NewbornInfectionsMaleNetherlandsPractice Guidelines as TopicPractice Patterns, Physicians'bacterial infectionschildfevergeneral practiceinfantreferral and consultationsigns and symptoms

Identifiers

PMID24567576
PMCPMC3876161

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.