ArticlePediatrics2014
Long-term outcomes of adolescents with juvenile-onset fibromyalgia in early adulthood.
Article in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it, 134 citations in OpenAlex.
- Systematic review and meta-analysis of the effect of psychological interventions on anxiety in children and youth with chronic medical conditions.Journal of pediatric psychology · 2025Pooled it
- Pilot Randomized Trial of Integrated Cognitive-Behavioral Therapy and Neuromuscular Training for Juvenile Fibromyalgia: The FIT Teens Program.The journal of pain · 2018Trial
- Trial
- Safety and efficacy of pregabalin in adolescents with fibromyalgia: a randomized, double-blind, placebo-controlled trial and a 6-month open-label extension study.Pediatric rheumatology online journal · 2016Trial
- Trial
- Empowered Relief for Youth: Development, feasibility and early effectiveness of a single session pain relief skills class.The journal of pain · 2026Article
- Targeted Real-Time Assessment of Chronic Pain (TRAC-Pain) in Youth: Protocol for a Digital Biosignature Development Through a Prospective Observational Cohort Study.JMIR research protocols · 2026Observational
- Cortical thickness, surface area, and multisite pain: distinct patterns by sex in adolescence.Biology of sex differences · 2026Article
- Examining Hope in Adolescents with Chronic Musculoskeletal Pain.Children (Basel, Switzerland) · 2026Article
- Differential Alterations in Offset Analgesia and Conditioned Pain Modulation in Fibromyalgia: Evidence for Distinct Central Dysregulation.European journal of pain (London, England) · 2026Article
- Why sleep matters in chronic pain: evidence across the lifespan.EBioMedicine · 2026Review
- PURSUIT Protocol: Development of a Novel Approach to Managing Youth Physical and Mental Health in Schools.Children (Basel, Switzerland) · 2026Article
- Exploring the perioperative experiences of youth undergoing cardiac surgery: A qualitative needs assessment for tailoring a mobile self-management app.Journal of clinical and translational science · 2026Article
- Network analysis in adolescent patients with somatic symptom disorders.BMC psychiatry · 2025Article
- The emergence of sex differences in primary pain during adolescence: a conceptual developmentally-oriented biopsychosocial model and opportunities for further investigation.BMC pediatrics · 2025Review
- I'm all over the place: complex symptom variability and within-day patterns among youth with chronic pain.Journal of behavioral medicine · 2025Article
- Patient subtyping in juvenile fibromyalgia: the role of multisensory hypersensitivity and neurophysiological correlates.Journal of pediatric psychology · 2025Article
- Parental opioid prescriptions and the risk of opioid use in adolescents and young adults: The HUNT Study linked with prescription registry data.PLoS medicine · 2025Article
- Juvenile Primary Fibromyalgia Syndrome: Advances in Etiopathogenesis, Clinical Assessment and Treatment: A Narrative Review.Biomedicines · 2025Review
- Sex, Neural Networks, and Behavioral Symptoms Among Adolescents With Multisite Pain.JAMA network open · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThis prospective longitudinal study examined the long-term physical and psychosocial outcomes of adolescents with juvenile-onset fibromyalgia (JFM), compared with healthy control subjects, into early adulthood.
methodsAdolescent patients with JFM initially seen at a pediatric rheumatology clinic (n = 94) and age- and gender-matched healthy control subjects (n = 33) completed online measures of demographic characteristics, pain, physical functioning, mood symptoms, and health care utilization at ∼6 years' follow-up (mean age: 21 years). A standard in-person tender-point examination was conducted.
resultsPatients with JFM had significantly higher pain (P < .001), poorer physical function (P < .001), greater anxiety (P < .001) and depressive symptoms (P < .001), and more medical visits (P < .001)than control subjects. The majority (>80%) of JFM patients continued to experience fibromyalgia symptoms into early adulthood, and 51.1% of the JFM sample met American College of Rheumatology criteria for adult fibromyalgia at follow-up. Patients with JFM were more likely than control subjects to be married and less likely to obtain a college education.
conclusionsAdolescent patients with JFM have a high likelihood of continued fibromyalgia symptoms into young adulthood. Those who met criteria for fibromyalgia in adulthood exhibited the highest levels of physical and emotional impairment. Emerging differences in educational attainment and marital status were also found in the JFM group. JFM is likely to be a long-term condition for many patients, and this study for the first time describes the wide-ranging impact of JFM on a variety of physical and psychosocial outcomes that seem to diverge from their same-age peers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.