Evidence map›Paper›PMID 24566980›Full record

ReviewNeurocritical care2014

Artery of Percheron infarction as an unusual cause of coma: three cases and literature review.

Nathalie Zappella, Sybille Merceron, Chantal Nifle, Julia Hilly-Ginoux, Fabrice Bruneel, Gilles Troché, Yves-Sebastien Cordoliani, Jean-Pierre Bedos, Fernando Pico, Stephane Legriel

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Neurocritical care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 58 citations in OpenAlex.

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  18. Artery of Percheron infarction: a case report.Journal of medical case reports · 2017
    Article
  19. Stroke Chameleons and Stroke Mimics in the Emergency Department.Current neurology and neuroscience reports · 2017
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nathalie ZappellaIntensive Care Unit, Centre Hospitalier de Versailles-Site André Mignot, 78150, Le Chesnay, France, nzap@live.fr.
Sybille Merceron
Chantal Nifle
Julia Hilly-Ginoux
Fabrice Bruneel
Gilles Troché
Yves-Sebastien Cordoliani
Jean-Pierre Bedos
Fernando Pico
Stephane Legriel
Centre Hospitalier de Versailles · FRHôpital Privé Jacques Cartier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveStroke due to occlusion of the artery of Percheron (AOP), an uncommon anatomic variant supplying the bilateral medial thalami, may raise diagnostic challenges and cause life-threatening symptoms. Our objective here was to detail the features and outcomes in three patients who required intensive care unit (ICU) admission and to review the relevant literature.

methodsDescription of three cases and literature review based on a 1973-2013 PubMed search.

resultsThree patients were admitted to our ICU with sudden-onset coma and respiratory and cardiovascular dysfunctions requiring endotracheal mechanical ventilation. Focal neurological deficits, ophthalmological signs (abnormal light reflexes and/or ocular motility and/or ptosis), and neuropsychological abnormalities were variably combined. Initial CT scan was normal. Cerebral MRI demonstrated bilateral paramedian thalamic infarction, with extension to the cerebral peduncles in two patients. Consciousness improved rapidly and time to extubation was 1-4 days. All three patients were discharged alive from the hospital and two had good 1-year functional outcomes. Similar clinical features and outcomes were recorded in the 117 patients identified in the literature, of whom ten required ICU admission.

conclusionsBilateral paramedian thalamic stroke due to AOP occlusion can be life threatening. The early diagnosis relies on MRI with magnetic resonance angiography. Recovery of consciousness is usually rapid and mortality is low, warranting full-code ICU management.

Indexed as

AgedAged, 80 and overArterial Occlusive DiseasesCerebral InfarctionCircle of WillisComaFemaleHumansMediodorsal Thalamic NucleusPosterior Cerebral Artery

Identifiers

PMID24566980
OpenAlexW2091493376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.