Evidence map›Paper›PMID 24566816›Full record

ArticleNature reviews. Endocrinology2014

Diabetes. Solving human β-cell development--what does the mouse say?

Alexandra E Folias, Matthias Hebrok

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature reviews. Endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexandra E FoliasDiabetes Center, Department of Medicine, University of California-San Francisco, 513 Parnassus Avenue, HSW 1116, Box 0540, San Francisco, CA 94143, USA.
Matthias HebrokDiabetes Center, Department of Medicine, University of California-San Francisco, 513 Parnassus Avenue, HSW 1116, Box 0540, San Francisco, CA 94143, USA.
University of California, San Francisco · US

Funding

Effects of Hedgehog Signaling on Pancreas OrganogenesisR01DK060533 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HEBROK, MATTHIAS · 2003 to 2012
$3.3M
NIDDK NIH HHS R01 DK060533
6 · The paper itself

Abstract

A genetic analysis of patients with permanent neonatal diabetes mellitus has revealed functional conservation of transcription factors critical for β-cell development in both mouse and man. This finding supports the use of mice for modelling human disease but also highlights the need for additional human-specific studies of β-cell function.

Indexed as

AnimalsDiabetes MellitusFemaleHomeodomain ProteinsHumansMaleMutationPancreasTranscription FactorsHomeodomain ProteinsTranscription Factors

Identifiers

PMID24566816
OpenAlexW2794153023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.