Evidence map›Paper›PMID 24566295›Full record

ReviewAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2014

Eosinophilic esophagitis.

Jamie Merves, Amanda Muir, Prasanna Modayur Chandramouleeswaran, Antonella Cianferoni, Mei-Lun Wang, Jonathan M Spergel

Open access · greenAbstract readReview
In one paragraph

Review in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Eosinophilic esophagitis during sublingual and oral allergen immunotherapy.Current opinion in allergy and clinical immunology · 2019
    Review
  7. Review
  8. Eosinophilic esophagitis: early diagnosis is the key.Clinical and experimental gastroenterology · 2019
    Article
  9. Review
  10. Allergic components of eosinophilic esophagitis.The Journal of allergy and clinical immunology · 2018
    Review
  11. Article
  12. Elevated expression of activated TAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2018
    Article
  13. Review
  14. Article
  15. Review
  16. Eosinophilic Esophagitis: A Comprehensive Review.Clinical reviews in allergy & immunology · 2016
    Review
  17. Role of Endoscopy in Diagnosis and Management of Pediatric Eosinophilic Esophagitis.Gastrointestinal endoscopy clinics of North America · 2016
    Review
  18. Wheat allergy: diagnosis and management.Journal of asthma and allergy · 2016
    Review
  19. From genetics to treatment of eosinophilic esophagitis.Current opinion in allergy and clinical immunology · 2015
    Article
  20. Eosinophilic Esophagitis and Gastroenteritis.Current allergy and asthma reports · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jamie MervesDivision of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Amanda MuirDivision of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Prasanna Modayur ChandramouleeswaranDivision of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Antonella CianferoniDivision of Allergy and Immunology, The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Mei-Lun WangDivision of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Jonathan M SpergelDivision of Allergy and Immunology, The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia. Electronic address: spergel@email.chop.edu.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

Toll-like Receptor Signaling in the Esophageal EpitheliumR01DK087789 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI SPERGEL, JONATHAN MICHEAL · 2010 to 2014
$1.8M
The role of iNKTs in eosinophilic esophagitis.K08AI089982 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI CIANFERONI, ANTONELLA · 2011 to 2013
$376k
NIAID NIH HHS K08 AI089982NIDDK NIH HHS R01 DK087789
6 · The paper itself

Abstract

objectiveTo review the understanding of the pathogenesis of eosinophilic esophagitis (EoE) and the role of the immune system in the disease process. DATA SOURCES: Peer-reviewed articles on EoE from PubMed searching for "Eosinophilic Esophagitis and fibrosis" in the period of 1995 to 2013. STUDY SELECTIONS: Studies on the clinical and immunologic features, pathogenesis, and management of EoE.

resultsRecent work has revealed that thymic stromal lymphopoietin and basophil have an increased role in the pathogenesis of disease. Additional understanding on the role of fibrosis in EoE is emerging.

conclusionThe incidence of EoE is increasing like most atopic disease. Similar to other allergic diseases, EoE is treated with topical steroids and/or allergen avoidance.

Indexed as

Adrenal Cortex HormonesAdultAllergensBasophilsChildCytokinesEosinophilic EsophagitisEosinophilsEsophagusFemaleGenetic Predisposition to DiseaseHumansLymphocytesMaleThymic Stromal LymphopoietinAdrenal Cortex HormonesAllergensCytokinesThymic Stromal Lymphopoietin

Identifiers

PMID24566295
PMCPMC4332835
OpenAlexW4254551568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.