Evidence map›Paper›PMID 24566233›Full record

Trial reportHeart rhythm2014

Utilization rates of implantable cardioverter-defibrillators for primary prevention of sudden cardiac death: a 2012 calculation for a midwestern health referral region.

Allen Hoang, Changyu Shen, James Zheng, Stanley Taylor, William J Groh, Marc Rosenman, Alfred E Buxton, Peng-Sheng Chen

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Heart rhythm, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Outcomes of catheter ablation in high-risk patients with Brugada syndrome refusing an implantable cardioverter defibrillator implantation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Allen HoangKrannert Institute of Cardiology and Division of Cardiology, Indiana University, Indianapolis, Indiana.
Changyu ShenDepartment of Biostatistics, Indiana University, Indianapolis, Indiana; The Regenstrief Institute, Indiana University, Indianapolis, Indiana.
James ZhengDepartment of Pediatrics, Indiana University, Indianapolis, Indiana.
Stanley TaylorDepartment of Biostatistics, Indiana University, Indianapolis, Indiana.
William J GrohKrannert Institute of Cardiology and Division of Cardiology, Indiana University, Indianapolis, Indiana.
Marc RosenmanRichard M. Fairbanks School of Public Health, Indiana University, Indianapolis, Indiana.
Alfred E BuxtonCardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Peng-Sheng ChenKrannert Institute of Cardiology and Division of Cardiology, Indiana University, Indianapolis, Indiana. Electronic address: chenpp@iupui.edu.
Indiana University – Purdue University Indianapolis · USHarvard University · USRegenstrief Institute · US

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
WAVE DYNAMICS IN NORMAL AND DISEASED RABBIT HEARTSP01HL078931 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHEN, PENG-SHENG · 2005 to 2015
$20.7M
Thoracic Veins and Sustained Atrial FibrillationR01HL071140 · NHLBI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CHEN, PENG-SHENG · 2002 to 2014
$4.7M
NCATS NIH HHS UL1 TR001108NHLBI NIH HHS P01 HL078931NHLBI NIH HHS P01HL78931NHLBI NIH HHS R01 HL071140PHS HHS R0171140
6 · The paper itself

Abstract

backgroundUtilization rates (URs) for implantable cardioverter-defibrillators (ICDs) for primary prevention of sudden cardiac death (PPSCD) are lacking in the community.

objectiveThe purpose of this study was to establish the ICD UR in central Indiana.

methodsA query run on 2 hospitals in a health information exchange database in Indianapolis identified patients between 2011 and 2012 with left ventricular ejection fraction (EF) ≤0.35. ICD eligibility and utilization were determined from chart review.

resultsWe identified 1863 patients with at least 1 low EF study. Two cohorts were analyzed: 1672 patients without and 191 patients with International Classification of Diseases, Ninth Revision, Clinical Modification procedure code 37.94 for ICD placement. We manually reviewed a stratified (by hospital) random sample of 300 patients from the no-ICD procedure code cohort and found that 48 (16%) had no ICD but had class I indications for ICD. Eight of 300 (2.7%) actually had ICD implantation for PPSCD. Review of all 191 patients in the ICD procedure code cohort identified 70 with ICD implantation for PPSCD. The ICD UR (ratio between patients with ICD for PPSCD and all with indication) was 38% overall (95% confidence interval [CI] 28%-49%). URs were 48% for males (95% CI 34%-61%), 21% for females (95% CI 16%-26%, P = .0002 vs males), 40% for whites (95% CI 27%-53%), and 37% for blacks (95% CI 28%-46%, P = .66 vs whites).

conclusionICD UR is 38% among patients meeting class I indications, suggesting further opportunities for improving guideline compliance. This study also illustrates limitations in calculating ICD UR using large electronic repositories without hands-on chart review.

Indexed as

Referral and ConsultationAdultAgedArrhythmias, CardiacConfidence IntervalsDeath, Sudden, CardiacDefibrillators, ImplantableFemaleFollow-Up StudiesHumansIncidenceIndianaMaleMiddle AgedPrimary PreventionPrognosisArrhythmiaDefibrillatorImplantable cardioverter-defibrillatorSudden cardiac deathUtilization

Identifiers

PMID24566233
PMCPMC4074531
OpenAlexW1967026481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.