ArticleAntimicrobial agents and chemotherapy2014
Characterization of blaOXA-143 variants in Acinetobacter baumannii and Acinetobacter pittii.
Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
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- Co-Existence of Carbapenemase-Encoding Genes in Acinetobacter baumannii from Cancer Patients.Infectious diseases and therapy · 2021Article
- Diversity of Oxacillinases and Sequence Types in Carbapenem-ResistantInternational journal of environmental research and public health · 2021Article
- Carbapenemases: TransformingBiomolecules · 2020Review
- Phenotypic Variation and Carbapenem Resistance Potential in OXA-499-ProducingFrontiers in microbiology · 2020Article
- Comparative Genomics ofFrontiers in microbiology · 2020Article
- Emergence and spread of carbapenem-resistant Acinetobacter baumannii international clones II and III in Lima, Peru.Emerging microbes & infections · 2018Article
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- Concentration and Variety of Carbapenemase Producers in Recreational Coastal Waters Showing Distinct Levels of Pollution.Antimicrobial agents and chemotherapy · 2017Article
- First Report of the Carbapenemase GeneAntimicrobial agents and chemotherapy · 2017Article
- Whole-Genome Sequence of a ColombianGenome announcements · 2017Article
- Co-existence ofAntimicrobial resistance and infection control · 2017Article
- Evaluation of a loop-mediated isothermal amplification-based methodology to detect carbapenemase carriage in Acinetobacter clinical isolates.Antimicrobial agents and chemotherapy · 2014Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The acquired carbapenem-hydrolyzing oxacillinase (OXA) OXA-143 has thus far been detected only in Acinetobacter baumannii isolates from Brazil. The aim of this study was to characterize three OXA-143 variants: OXA-231 and OXA-253 from carbapenem-resistant A. baumannii isolates and OXA-255 in a carbapenem-susceptible Acinetobacter pittii isolate originating from Brazil, Honduras, and the United States, respectively. The 5' rapid amplification of cDNA ends (RACE) technique identified the same transcription initiation site for all blaOXA-143-like genes and revealed differences in the putative promoter regions. However, all cloned OXA-143 variants conferred carbapenem resistance on A. baumannii ATCC 17978 and OXA-255 conferred carbapenem resistance on A. pittii SH024, which was correlated with blaOXA-255 gene expression. This is the first description of OXA-143-like outside A. baumannii. Detection of OXA-143-like in the United States and Honduras indicates its dissemination through the American continent.
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