ArticleInternational journal of molecular sciences2014
The glutathione peroxidase gene family in Thellungiella salsuginea: genome-wide identification, classification, and gene and protein expression analysis under stress conditions.
Article in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 59 citations in OpenAlex.
- Article
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- The Glutathione Peroxidase Gene Family inAntioxidants (Basel, Switzerland) · 2025Article
- Characterization ofInternational journal of molecular sciences · 2024Article
- The ascorbate-glutathione cycle coming of age.Journal of experimental botany · 2024Review
- Overexpression ofGenes · 2024Article
- Redox Regulation of Salt Tolerance inInternational journal of molecular sciences · 2023Article
- The Glutathione Peroxidase Gene Family inGenes · 2023Article
- Plant Glutathione Peroxidases: Non-Heme Peroxidases with Large Functional Flexibility as a Core Component of ROS-Processing Mechanisms and Signalling.Antioxidants (Basel, Switzerland) · 2022Review
- Crosstalk between theInternational journal of molecular sciences · 2022Article
- Adaptative Mechanisms of HalophyticFrontiers in plant science · 2022Review
- Genome-Wide Characterization of Glutathione Peroxidase (GPX) Gene Family in Rapeseed (Antioxidants (Basel, Switzerland) · 2021Article
- Evolutionary and functional analyses demonstrate conserved ferroptosis protection by Arabidopsis GPXs in mammalian cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Identification of Glutathione Peroxidase Gene Family inFrontiers in plant science · 2021Article
- Trehalose Protects Maize Plants from Salt Stress and Phosphorus Deficiency.Plants (Basel, Switzerland) · 2019Article
- Intracellular catalase activity instead of glutathione level dominates the resistance of cells to reactive oxygen species.Cell stress & chaperones · 2019Article
- Identification of Glutathione Peroxidase (GPX) Gene Family inInternational journal of molecular sciences · 2018Article
- Genome-wide identification of glutathione peroxidase (GPX) gene family and their response to abiotic stress in cucumber.3 Biotech · 2018Article
- Overexpression of the Glutathione Peroxidase 5 (Frontiers in plant science · 2018Article
- Nostoc calcicola extract improved the antioxidative response of soybean to cowpea aphid.Botanical studies · 2017Article
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Authors and funding
8 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Glutathione peroxidases (GPX) catalyze the reduction of H2O2 or organic hydroperoxides to water or corresponding alcohols using reduced glutathione, which plays an essential role in ROS (reactive oxygen species) homeostasis and stress signaling. Thellungiella salsuginea (Eutrema salsugineum), a relative of Arabidopsis thaliana, displays an extremely high level of tolerance to salt, drought, cold and oxidative stresses. The enzymatic antioxidant systems may contribute to the stress tolerance of T. salsuginea. In the present study, we aimed at understanding the roles of the antioxidant enzymes in T. salsuginea by focusing on the GPX family. We identified the eight GPX genes in T. salsuginea, and the structure of the N-terminal domains indicated their putative chloroplastic, mitochondrial and cytoplasmic location. The exon-intron organization of these genes exhibited a conserved pattern among plant GPX genes. Multiple environmental stresses and hormone response related cis-acting elements were predicted in the promoters of TsGPX genes. The gene and protein expression profiles of TsGPXs in response to high level of salinity and osmotic stresses, in leaves and roots of T. salsuginea were investigated using real-time RT-PCR and western blotting analysis. Our result showed that different members of the GPX gene family were coordinately regulated under specific environmental stress conditions, and supported the important roles of TsGPXs in salt and drought stress response in T. salsuginea.
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