Trial reportThe journal of allergy and clinical immunology. In practice
The impact of peer support and mp3 messaging on adherence to inhaled corticosteroids in minority adolescents with asthma: a randomized, controlled trial.
Trial report in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07224061 (Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination in Clinics and Schools), which is not on this map. Cited by 22 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination in Clinics and Schools (PRAGMATIC-S)
Who cites it
22 citing papers in PubMed, 8 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Remote monitoring in asthma: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Digital interventions to improve adherence to maintenance medication in asthma.The Cochrane database of systematic reviews · 2022Pooled it
- Features of successful interventions to improve adherence to inhaled corticosteroids in children with asthma: A narrative systematic review.Pediatric pulmonology · 2022Pooled it
- Meta-Analysis of Adherence Promotion Interventions in Pediatric Asthma.Journal of pediatric psychology · 2021Pooled it
- Systematic Review of Digital Interventions for Pediatric Asthma Management.The journal of allergy and clinical immunology. In practice · 2020Pooled it
- Culture-specific programs for children and adults from minority groups who have asthma.The Cochrane database of systematic reviews · 2017Pooled it
- Lay-led and peer support interventions for adolescents with asthma.The Cochrane database of systematic reviews · 2017Pooled it
- Interventions to improve adherence to inhaled steroids for asthma.The Cochrane database of systematic reviews · 2017Pooled it
- A randomised controlled trial of the effect of a connected inhaler system on medication adherence in uncontrolled asthmatic patients.The European respiratory journal · 2021Trial
- The Detroit Young Adult Asthma Project: Pilot of a Technology-Based Medication Adherence Intervention for African-American Emerging Adults.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2016Trial
- A Comprehensive Scoping Review of Technology in the Care of Historically Marginalized Populations With Asthma: A Work Group Report of the AAAAI Diversity, Equity, and Inclusion Committee.The journal of allergy and clinical immunology. In practice · 2025Article
- eHealth Technologies for Monitoring Pediatric Asthma at Home: Scoping Review.Journal of medical Internet research · 2023Article
- Measurement of adherence to inhaled corticosteroids by self-report and electronic medication monitoring.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023Article
- Advancing Digital Solutions to Overcome Longstanding Barriers in Asthma and COPD Management.Patient preference and adherence · 2023Review
- Adherence and Self-management Interventions among Systemically Marginalized and Underserved Youth with Asthma.Clinical practice in pediatric psychology · 2022Article
- Digital health interventions in children with asthma.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021Article
- Design and baseline characteristics of a low-income urban cohort of children with asthma: The Asthma Action at Erie Trial.Contemporary clinical trials · 2019Article
- Cultural Issues in Medication Adherence: Disparities and Directions.Journal of general internal medicine · 2018Review
- Interventions on Adherence to Treatment in Children With Severe Asthma: A Systematic Review.Frontiers in pediatrics · 2018Article
- Interventions to Improve Management of Chronic Conditions Among Racial and Ethnic Minorities.Journal of racial and ethnic health disparities · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPoor adherence to inhaled corticosteroids (ICS) is a critical risk factor contributing to asthma morbidity among low-income minority adolescents.
objectiveThis trial tested whether peer support group meetings and peer asthma messages delivered via mp3 players improved adherence to ICS.
methodsLow-income African American and/or Hispanic adolescents, ages 11-16 years old, with persistent asthma, and poor (≤ 48%) adherence to prescription ICS during the 3-week run-in were randomized to intervention or attention control groups (ATG) for the 10-week treatment. During treatment, the intervention arm subjects participated in weekly coping peer group support sessions and received mp3 peer-recorded asthma messages that promoted adherence. The ATG participated in weekly meetings with a research assistant and received an equivalent number of mp3 physician-recorded asthma messages. Adherence was measured by using self-report and the Doser CT, an electronic dose counter. The primary outcome was the difference in adherence at 10 weeks between the 2 arms.
resultsThirty-four subjects were randomized to each arm. At 10 weeks, no statistical difference in objectively measured adherence could be detected between the 2 arms when adjusting for baseline adherence (P = .929). Adherence declined in both groups over the course of the active treatment period. In both study arms, self-reported adherence by participants was significantly higher than their objectively measured adherence at week 10 (P < .0001).
conclusionImproving medication adherence in longitudinal studies is challenging. Peer support and mp3-delivered peer asthma messages may not be of sufficient dose to improve outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.