Evidence map›Paper›PMID 24565508›Full record

ArticleThe Journal of surgical research2014

Long-term diabetic response to gastric bypass.

Stephen W Davies, Jimmy T Efird, Christopher A Guidry, Rachel I Penn, Robert G Sawyer, Bruce D Schirmer, Peter T Hallowell

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of surgical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stephen W DaviesDepartment of General Surgery, University of Virginia School of Medicine, Charlottesville, Virginia. Electronic address: sd2wf@virginia.edu.
Jimmy T EfirdDepartment of Public Health, Biostatistics Unit, Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
Christopher A GuidryDepartment of General Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
Rachel I PennUniversity of Miami Miller School of Medicine, Miami, Florida.
Robert G SawyerDepartment of General Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
Bruce D SchirmerDepartment of General Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
Peter T HallowellDepartment of General Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
University of Virginia · USEast Carolina University · USUniversity of Miami · US

Funding

Surgical Infectious Diseses and Transplantation Training GrantT32AI078875 · NIAID · UNIVERSITY OF VIRGINIA · PI SAWYER, ROBERT G · 2009 to 2013
$947k
NIAID NIH HHS T32 AI078875
6 · The paper itself

Abstract

backgroundAs obesity and type II diabetes continue to rise, bariatric surgery offers a solution, but few long-term studies are available. The purpose of this study was to evaluate the long-term outcomes of diabetic patients after gastric bypass. MATERIALS AND

methodsThis was a retrospective cohort study of all diabetic patients undergoing gastric bypass at our institution, from 1998 to 2012. Patients were compared by postoperative diabetic response to treatment (i.e., response = off oral medication/insulin versus refractory = on oral medication/insulin) and followed at 1-, 3-, 5-, and 10-y intervals. Continuous data were analyzed using Student t-test or Wilcoxon rank-sum test. Multivariable, Cox proportional hazard regression model was performed to compute diabetic cure ratios and 95% confidence intervals.

resultsA total of 2454 bariatric surgeries were performed at our institution during the time period. A total of 707 diabetic patients were selected by Current Procedural Terminology codes for gastric bypass. Mean follow-up was 2.1 y. Incidence of diabetic response was 56% (1 y), 58% (3 y), 60% (5 y), and 44% (10 y). Postoperatively, responsive patients experienced greater percentage of total body weight loss (1 y [P < 0.0001], 3 y [P = 0.0087], and 5 y [P = 0.013]), and less hemoglobin A1c levels (1 y [P = 0.035] and 3 y [P = 0.040]) at follow-up than refractory patients. Multivariable analysis revealed a significant, independent inverse trend in incidence of diabetic cure as both age and body mass index decreased (Ptrend = 0.0019 and <0.0001, respectively). In addition, degenerative joint disease was independently associated with responsive diabetes (cure ratio = 1.6 [95% confidence interval = 1.1-2.2]).

conclusionsAt follow-up, both groups in our study experienced substantial weight loss; however, a greater loss was observed among the response group. Further research is needed to evaluate methods for optimizing patient care preoperatively and improving patient follow-up.

Indexed as

Gastric BypassAdultDiabetes ComplicationsFemaleFollow-Up StudiesHumansMaleMiddle AgedObesity, MorbidRetrospective StudiesWeight LossDiabetesDiabetes cureGastric bypassLong-term follow-up

Identifiers

PMID24565508
PMCPMC4096603
OpenAlexW2079784133

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.