ReviewJournal of studies on alcohol and drugs. Supplement2014
Seventy-five years of comorbidity research.
Review in Journal of studies on alcohol and drugs. Supplement, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Drinking to cope with negative emotions moderates alcohol use disorder treatment response in patients with co-occurring anxiety disorder.Drug and alcohol dependence · 2016Trial
- Development of a Multi-Organ Microphysiological (MPS) Model to Study Age-Related Comorbidities.Advanced biology · 2026Article
- Evidence for an alcohol-related "harm paradox" in individuals with internalizing disorders: Test and replication in two independent community samples.Alcohol, clinical & experimental research · 2023Article
- An integrated multimodal model of alcohol use disorder generated by data-driven causal discovery analysis.Communications biology · 2021Article
- Causal Network Modeling of the Determinants of Drinking Behavior in Comorbid Alcohol Use and Anxiety Disorder.Alcoholism, clinical and experimental research · 2019Article
- A network approach to modeling comorbid internalizing and alcohol use disorders.Journal of abnormal psychology · 2017Article
- Beyond comorbidity: Toward a dimensional and hierarchical approach to understanding psychopathology across the life span.Development and psychopathology · 2016Article
- Adolescent Social Isolation as a Model of Heightened Vulnerability to Comorbid Alcoholism and Anxiety Disorders.Alcoholism, clinical and experimental research · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
objectiveAs part of the 75th anniversary edition of the Journal of Studies on Alcohol and Drugs, this article reviews research on the relationship between mental disorders and substance use disorders ("comorbidity") from 1940--the journal's inception--to the present.
methodFirst, a survey of the titles and abstracts of all articles published in the journal was used to identify those articles pertaining to comorbidity. Seminal and representative works from this set of articles and a limited selection of articles from other journals were included in the review.
resultsThe early psychosocial research emphasized psychoanalytic formulations of alcohol use as a defensive symptom, which informed the early experimental research on the tension-reducing properties of alcohol. The "cognitive revolution," occurring in the 1970s, enabled an expansion of the tension-reduction theory to include a central role for mental processes (e.g., alcohol expectancies) in promoting drinking to cope with negative affectivity. The early clinical research characterized mental conditions commonly co-occurring with alcohol disorders and considered their etiological relationship to alcohol disorders. The "neo-Kraepelinian revolution" in psychiatry, which also occurred in the 1970s, infused the clinical comorbidity research with a more rigorous diagnostic technology and a range of biomedical research methodologies to study the mechanistic linkages of co-occurring disorders.
conclusionsAlthough a substantial quantity of scientific information on comorbidity has accumulated over the past 75 years, a standard model(s) of comorbidity has yet to congeal. Barriers and opportunities related to achieving this important goal are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.