Evidence map›Paper›PMID 24563807›Full record

ArticleJournal of cancer therapy2013

Cks1: Structure, Emerging Roles and Implications in Multiple Cancers.

Vinayak Khattar, Jaideep V Thottassery

Open access · diamondAbstract read
In one paragraph

Article in Journal of cancer therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Regulation of Transient Site-specific Copy Gain by MicroRNA.The Journal of biological chemistry · 2016
    Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vinayak KhattarSouthern Research Institute, Birmingham, USA.
Jaideep V ThottasserySouthern Research Institute, Birmingham, USA ; University of Alabama Comprehensive Cancer Center, Birmingham, USA.
Southern Research Institute · US

Funding

GENETIC MECHANISMS OF BREAST TUMOR PROGRESSIONR01CA050376 · NCI · SOUTHERN RESEARCH INSTITUTE · PI KERN, FRANCIS G. · 1989 to 2004
$2.3M
NCI NIH HHS R01 CA050376
6 · The paper itself

Abstract

Deregulation of the cell cycle results in loss of normal control mechanisms that prevent aberrant cell proliferation and cancer progression. Regulation of the cell cycle is a highly complex process with many layers of control. One of these mechanisms involves timely degradation of CDK inhibitors (CKIs) like p27

Indexed as

Cdk1CKICks1Cks2ERK1/2Kip1p130p27ProteasomeRb2Skp2Ubiquitination

Identifiers

PMID24563807
PMCPMC3930463
OpenAlexW2006043249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.